Cloning and expression pattern of gsdf during the first maleness reproductive phase in the protandrous Acanthopagrus latus

General and Comparative Endocrinology
Yuan ChenShi Xi Chen

Abstract

Gonadal soma-derived factor (Gsdf) is a new member of the transforming growth factor beta superfamily. As a teleost- and gonad-specific growth factor, several studies indicate that Gsdf plays an important role in early germ cell development. In the present study, for the first time, a 1700-bp long gsdf gene was cloned from a protandrous species, Acanthopagrus latus. We further analyzed the cellular localization and the expression patterns of gsdf in respective testicular and ovarian zones during the first maleness reproductive phase. The results showed that gsdf transcripts were highly expressed in the ovotestis during sex differentiation, and the somatic cells of the testicular zone expressed many more gsdf transcripts than those of the ovarian zone. At the onset of puberty, the gsdf expression levels decreased gradually during spermatogenesis. Conversely, the ovarian zone exhibited a stable increase pattern which was similar to the plasma 17β-estradiol (E2) levels. These results suggested that Gsdf may participates in early germ cell development, e.g. proliferation and differentiation of spermatogonia and oogonia in A. latus.

References

Aug 10, 2007·Biology of Reproduction·Chiemi MiuraTakeshi Miura
Apr 8, 2009·General and Comparative Endocrinology·Rüdiger W SchulzTakeshi Miura
Sep 11, 2009·Biology of Reproduction·Shi X ChenRüdiger W Schulz
Oct 29, 2011·Biology of Reproduction·Guan-Chung WuChing-Fong Chang
Mar 14, 2012·Fish Physiology and Biochemistry·Guan-Chung Wu, Ching-Fong Chang
Jan 22, 2013·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Ryo HoriguchiMasaru Nakamura

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Citations

Mar 31, 2016·Molecular Reproduction and Development·Dong-Neng JiangDe-Shou Wang
Sep 1, 2017·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Yi-Lin YanJohn Postlethwait
Nov 13, 2020·Physiological Reviews·Yoshitaka NagahamaMasaru Nakamura
Jul 27, 2021·Frontiers in Cell and Developmental Biology·Chen-Wei Hsu, Bon-Chu Chung

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