Cloning and sequencing of a cDNA for Akazara scallop troponin T

Journal of Biochemistry
A InoueKiyoyoshi Nishita

Abstract

A cDNA clone encoding troponin T of Akazara scallop (Chlamys nipponensis akazara) striated adductor muscle has been isolated and sequenced. The complete sequence deduced consists of 314 amino acid residues with a molecular weight of 37,206. Akazara scallop troponin T contains 55 amino acid residues more and 82 residues fewer than rabbit skeletal muscle troponin T and Drosophila melanogaster troponin T, respectively, showing almost the lowest sequence homology with rabbit troponin T (26%) but the highest homology with Drosophila troponin T (33%). Further, high sequence homology was seen in the functional regions: residues 33-120 and 174-227, corresponding respectively to residues 71-158 and 197-250 of rabbit troponin T (tropomyosin-binding regions); and residues 200-204, corresponding to 223 227 of rabbit troponin T (troponin I-binding region). In residues 1-70 (tropomyosin-binding region), however, only six residues are identical with rabbit troponin T.

Citations

Oct 16, 2013·Zoological Science·Daisuke FunabaraSatoshi Kanoh
Aug 10, 2010·Journal of Invertebrate Pathology·Marie-Agnès TraversChristine Paillard
Sep 9, 2008·Journal of Molecular Biology·Hyun Suk Jung, Roger Craig
May 6, 2008·Biochimica Et Biophysica Acta·Hiroyuki TanakaTakao Ojima
Nov 18, 2005·Biochemical and Biophysical Research Communications·Fumiaki YumotoIwao Ohtsuki
Dec 27, 2005·Biochemical and Biophysical Research Communications·Tomoki AiharaToshiaki Arata
May 23, 2003·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Chung-Der HsiaoHuai-Jen Tsai
Jul 1, 2005·Physiological Reviews·Scott L Hooper, Jeffrey B Thuma
Oct 23, 2010·Archives of Biochemistry and Biophysics·Bin Wei, J-P Jin

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