PMID: 9540828Apr 16, 1998Paper

Cloning and sequencing of the cDNA encoding human neurotrypsin

Biochimica Et Biophysica Acta
K ProbaPeter Sonderegger

Abstract

cDNA clones encoding human neurotrypsin have been isolated from a human fetal brain cDNA library using a PCR-amplified probe. The assembled cDNA sequence contains a 2625 bp open reading frame encoding a multidomain serine protease with an overall sequence identity of 82.5% to murine neurotrypsin. Surprisingly, the human neurotrypsin exhibits an additional scavenger receptor cysteine-rich repeat.

References

Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
Jun 11, 1986·Nucleic Acids Research·G von Heijne
Feb 7, 1995·Biochemistry·J J PeronaR J Fletterick
Jan 1, 1994·Trends in Biochemical Sciences·D ResnickM Krieger
Aug 1, 1993·The Journal of Clinical Investigation·A P SappinoJ D Vassalli
Jan 1, 1996·Brain Research. Molecular Brain Research·T Masos, R Miskin
Jan 1, 1997·Molecular and Cellular Neurosciences·T P GschwendP Sonderegger

❮ Previous
Next ❯

Citations

Jan 26, 2000·Insect Biochemistry and Molecular Biology·M J GormanS M Paskewitz
Jun 28, 2014·Trends in Neurosciences·Peter Sonderegger, Kazumasa Matsumoto-Miyai
Jan 7, 2016·Annals of Clinical and Translational Neurology·Shiyong PengAnil B Mukherjee
Jun 26, 2008·Protein Expression and Purification·Raymond ReifPeter Sonderegger
Aug 20, 2003·Human Molecular Genetics·Florence MolinariLaurence Colleaux
Oct 15, 2010·Nature Reviews. Neuroscience·Alexander DityatevPeter Sonderegger
Feb 13, 2019·Protein Science : a Publication of the Protein Society·Anselmo CancianiFederico Forneris
Jan 31, 2008·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Alexander StephanPeter Sonderegger
Jun 26, 2007·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Raymond ReifPeter Sonderegger
Sep 2, 2011·Pharmacological Reviews·Vanesa Gabriela MartínezFrancisco Lozano
Jan 31, 2020·Frontiers in Molecular Biosciences·Salvatore R GuarinoFederico Forneris
Apr 16, 2020·Critical Reviews in Biochemistry and Molecular Biology·Lise BoonGhislain Opdenakker

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.