PMID: 9435108Jan 22, 1998Paper

Cloning of a cDNA fragment encoding part of the protein moiety of the 58-kDa fibrinogen-binding mannoprotein of Candida albicans

FEMS Microbiology Letters
J L Lopez-RibotJ P Martínez

Abstract

Immunoscreening of a Candida albicans expression library with antibodies against the 58 kDa fibrinogen-binding mannoprotein (mp58) of the fungus resulted in the isolation of clones encoding the protein moiety of this molecule. Sequence of the 0.9 kb cDNA of one of the clones selected for further analysis, revealed an open reading frame coding for 292 amino acids, which displays sequence similarity to proteins belonging to a family of immunodominant antigens of Aspergillus spp. The gene corresponding to this cDNA was named FBP1 (fibrinogen-binding protein). These results represent the first report on the identification of C. albicans genes encoding surface receptors for host proteins.

Citations

Jun 26, 2001·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·B BanerjeeJ N Fink
Jul 16, 2008·Infection and Immunity·A MarcilM Whiteway
Jan 20, 2011·Infection and Immunity·Dmitry A SolovievWilliam A Fonzi
Jul 5, 2012·PLoS Pathogens·Francesco CitiuloDuncan Wilson
Sep 27, 2006·Proteomics·Derek P ThomasJose L Lopez-Ribot
Aug 25, 1999·Current Opinion in Microbiology·P Sundstrom
Jun 16, 2004·FEMS Immunology and Medical Microbiology·José L López-RibotJosé P Martínez
Mar 31, 2005·FEMS Microbiology Letters·Véronique MarchaisJane Cottin
Apr 12, 2000·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·R D Cannon, W L Chaffin
Jul 31, 2012·The Journal of Immunology : Official Journal of the American Association of Immunologists·Samir JawharaDmitry A Soloviev

❮ Previous
Next ❯

Related Concepts

Related Feeds

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.