Cloning of the cDNA encoding a novel subtype of histone H1

Gene
T Yamamoto, M Horikoshi

Abstract

The H1 class of histones is implicated in organizing a higher order of chromatin structure and in involvement with transcriptional repression. They compromise multiple subtypes that presumably have a specific function. We report here the isolation and characterization of a human cDNA encoding a novel subtype of histone H1. It is the most distantly related subtype of mammalian H1 reported to date. However, it still shares the characteristic features of H1: the tripartite structure, conservation in the globular domain, the profile of hydropathy and the basic isoelectric point. The expression of this H1 subtype was ubiquitously observed in all tissues examined. Our findings suggest that novel subtypes of H1 may remain unidentified in mammals.

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Citations

Oct 29, 2003·Journal of Biotechnology·Iratxe PueblaWalter Low
Mar 17, 2005·Bioinformatics·Rajesh ChowdharyVladimir B Bajic
Aug 16, 2013·Nucleic Acids Research·Sean W HarshmanMichael A Freitas
Aug 29, 2006·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Missag H Parseghian, Keith A Luhrs
Feb 24, 2009·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Nikhil RaghuramMichael J Hendzel
Jul 12, 2005·Biological Chemistry·Nicole HappelDetlef Doenecke
Dec 29, 2011·Frontiers in Bioscience (Landmark Edition)·Magdalena MedrzyckiYuhong Fan
Dec 23, 2015·Biochimica Et Biophysica Acta·Chenyi Pan, Yuhong Fan
Sep 18, 2007·Biology of the Cell·Stefan StoldtNicole Happel
Sep 10, 2013·Journal of Proteomics·Sean W HarshmanMichael A Freitas
Aug 3, 2017·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Keiko Ichihara-TanakaSatoshi Kishida
Jan 6, 2021·Genes & Development·Laura Prendergast, Danny Reinberg
Jun 26, 2009·Journal of Proteome Research·Aiping LuJacek R Wiśniewski
Dec 15, 2004·Journal of Proteome Research·Benjamin A GarciaDonald F Hunt

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