PMID: 3762692DOI: 10.1038/323411a0Oct 2, 1986Paper
Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor
Nature
T KuboK Kangawa
Abstract
Cloning and sequence analysis of DNA complementary to porcine cerebral messenger RNA encoding the muscarinic acetylcholine receptor predict the complete amino-acid sequence of this protein. Expression of the complementary DNA produced functional muscarinic receptor in Xenopus oocytes. The muscarinic receptor is homologous with the beta-adrenergic receptor and rhodopsin in both amino-acid sequence and suggested transmembrane topography.
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