Closed-loop stimulation as a physiological rate-modulated pacing approach based on intracardiac impedance to lower the atrial tachyarrhythmia burden in patients with sinus node dysfunction and atrial fibrillation.

Journal of Cardiovascular Electrophysiology
Shota IkedaHiroyuki Tsutsui

Abstract

The effectiveness of rate-modulated pacing for the suppression of atrial fibrillation (AF) is controversial. Closed-loop stimulation (CLS) is a heart rate modulation technique based on the contractility of the right ventricle estimated by sensing myocardial impedance, and CLS can still adapt to the heart rate in conditions where there are no significant changes in acceleration or ventilation, such as emotional stress. We elucidated the association between CLS and atrial tachyarrhythmia (AT) burden in patients with sinus node dysfunction and paroxysmal AF history before pacemaker implantation. We retrospectively reviewed all consecutive patients who underwent pacemaker implantation for sinus node dysfunction with an AF history before implantation. Overall, 146 patients were analyzed, with fixed-rate pacing (FP) in 82, CLS in 31, and non-CLS rate modulation in 33 patients. The AF/AT episodes were detected in 98 patients during a 12-month period. The median AF/AT burden was 1.6% (interquartile: 0.0%, 11.0%) in FP; 0% (0.0%, 2.5%) in CLS, and 1.0% (0.1%, 9.3%) in non-CLS. The AF/AT burden was significantly lower for CLS than for FP and non-CLS rate modulation (P < .01 and P = .04, respectively). CLS was associated with lower risks ...Continue Reading

References

Nov 1, 1992·Pacing and Clinical Electrophysiology : PACE·M Schaldach, H Hutten
Feb 1, 1991·Pacing and Clinical Electrophysiology : PACE·P E VardasR Sutton
Jan 15, 2004·Pacing and Clinical Electrophysiology : PACE·Massimo SantiniVincenzo Barbaro
Mar 1, 2005·Pacing and Clinical Electrophysiology : PACE·Fabrizio DragoVincenzo Barbaro
May 3, 2006·Pacing and Clinical Electrophysiology : PACE·Jay ChenMohamed H Hamdan
Mar 6, 2007·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kenneth A Ellenbogen
Aug 3, 2007·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Willem de VoogtChu-Pak Lau
Sep 4, 2007·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Gervasio A LamasDaniel B Mark
Nov 6, 2009·Pacing and Clinical Electrophysiology : PACE·Raffaele QuaglionePietro Bartolini
Jan 26, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Tatsuya KawasakiHiroki Sugihara
Jan 7, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Rick A VeaseyA Neil Sulke
Aug 9, 2011·Pacing and Clinical Electrophysiology : PACE·Lior U ElkayamGervasio A Lamas
Jul 23, 2013·Circulation. Arrhythmia and Electrophysiology·Irene GrundvoldJohan Bodegard
Apr 26, 2014·Circulation Research·Peng-Sheng ChenStanley Nattel
Jun 11, 2014·International Journal of Cardiology·Basri AmasyaliCelal Kilit
May 12, 2016·Circulation·Roy M John, Saurabh Kumar
Dec 15, 2016·Journal of Cardiovascular Electrophysiology·Cristina GalloFiorenzo Gaita
Apr 30, 2017·JACC. Clinical Electrophysiology·Wesley T O'NealMouaz H Al-Mallah

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Citations

Mar 7, 2021·The Veterinary Journal·N Sydney MoïseRomain Pariaut

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