Closing-in in Parkinson's disease individuals with dementia: An experimental study

Journal of Clinical and Experimental Neuropsychology
Natascia de LuciaLuigi Trojano

Abstract

The tendency to reproduce figures close to or superimposed on the model in copying tasks, the so-called Closing-in (CI) phenomenon, has been rarely reported in individuals affected by Parkinson's disease and associated dementia (PD-D). We aimed to comprehend the genesis of CI in PD-D individuals by assessing whether reduction of attention/executive resources can increase the tendency to deviate toward the model. Thirty PD-D individuals underwent a neuropsychological evaluation exploring visuo-spatial, visuo-constructional, executive and memory abilities. An experimental copying task was employed in single and in two dual task conditions to assess whether a (verbal) cognitive load can increase CI in these individuals, compared with a matched sample of healthy adults. CI occurred in 19/30 (63.3%) PD-D individuals: 4 of them produced copies close to the model (near-CI), whereas 15 individuals also superimposed their copies on the model (adherent-CI) besides showing near-CI. Presence of CI in PD-D individuals was significantly correlated with executive dysfunction but not with general cognitive impairment. In the experimental copying task the tendency to deviate toward the model was strongly correlated with executive dysfunction, a...Continue Reading

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May 6, 2015·Parkinsonism & Related Disorders·Natascia De LuciaGabriella Santangelo

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Citations

Apr 23, 2016·Journal of Alzheimer's Disease : JAD·Luigi Trojano, Guido Gainotti
Nov 8, 2016·Alzheimer Disease and Associated Disorders·Natascia De LuciaLuigi Trojano
Dec 5, 2017·Journal of the International Neuropsychological Society : JINS·Natascia De LuciaLuigi Trojano
Oct 19, 2017·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Costanza Papagno, Luigi Trojano
Mar 20, 2018·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Natascia De LuciaGiuseppe De Michele

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