Clostridium difficile infection of the small bowel--two case reports with a literature survey.

International Journal of Colorectal Disease
Christoph HolmerJörg-Peter Ritz

Abstract

Diseases associated with Clostridium difficile range from antibiotic-related diarrhea to pseudomembranous enterocolitis, and are serious nosocomial infections with high morbidity and mortality. The C. difficile infection has thus far been regarded as a disease typically affecting the colon. However, the literature contains an increasing number of reports describing infections of the small bowel with fulminant clinical courses and high mortality rates of 60-83%. We think this situation is not very well known. We present two cases of confirmed C. difficile enteritis and a survey of the literature. C. difficile enteritis is characterized by a rising incidence, a sometimes fulminant clinical course, and high mortality rates. Early diagnosis of the disease by toxin detection and endoscopy is of paramount importance and can play a substantial role in improving outcomes.

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Aug 13, 2013·The Journal of Infectious Diseases·Sarah A KuehneNigel P Minton
Mar 13, 2014·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·S KilleenD C Winter
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Nov 18, 2014·Inflammatory Bowel Diseases·Darren N Seril, Bo Shen
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Mar 11, 2011·Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine·Kiyotaka OkawaKoji Sano

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