Clostridium septicum aortitis and colon carcinoma

Journal of Cardiovascular Computed Tomography
Daniel J Mizrahi, Ethan J Halpern

Abstract

Clostridium septicum (C. septicum) aortitis is a rare but highly fatal infection that has a strong association with occult malignancy. Aneurysmal transformation of C. septicum aortitis is common and has been reported to occur in as little as 1 to 3 weeks. We report a case of C. septicum Aortitis with concomitant adenocarcinoma of the ascending colon detected via CT scan. Imaging findings of colonic malignancy with aortitis are highly suggestive of infection with C. septicum. Given the high associated mortality and rapid progression, early recognition on imaging could have life saving implications. Additionally, imaging findings of aortitis in conjunction with C. septicum bacteremia should prompt the careful evaluation for malignancy, most notably colonic or hematologic.

References

Jul 21, 1969·JAMA : the Journal of the American Medical Association·R J Alpern, V R Dowell
Mar 25, 2009·Journal of Vascular Surgery·Christopher W SederPaul Bove

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Citations

Aug 30, 2018·Scottish Medical Journal·Gareth TurnbullMartin Sarungi
Apr 26, 2020·Clinical Nuclear Medicine·Nicolas PlouznikoffPatrick Flamen

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