Clozapine for the treatment of adolescents with schizophrenia

Journal of the American Academy of Child and Adolescent Psychiatry
B BirmaherR Ganguli

Abstract

Despite recent reports that clozapine is useful for the treatment of chronic schizophrenics resistant to neuroleptics, no studies have been reported in adolescents with schizophrenia. Despite the risk of potentially fatal agranulocytosis, clozapine's use in adolescents may become important because of its lack of extrapyramidal side effects or association with tardive dyskinesia, and reports that suggest that schizophrenic adolescents resemble chronic adult schizophrenics. The authors report three successful trials of clozapine in adolescents with schizophrenia who did not respond to conventional neuroleptic treatment.

References

Jun 1, 1979·Archives of General Psychiatry·A WelnerR Fishman
Jan 1, 1990·Acta Psychiatrica Scandinavica. Supplementum·P Seeman
Jan 1, 1989·Psychopharmacology·D E Casey
Dec 1, 1987·Journal of Clinical Psychopharmacology·J ClaghornG Klerman
Jul 1, 1980·The Journal of Nervous and Mental Disease·K WhiteD Deandrea
Aug 1, 1980·The American Journal of Psychiatry·H L KlawansS Perlik
Jan 1, 1983·Clinical Neuropharmacology·M CampbellW G Bennett
Mar 1, 1984·The American Journal of Psychiatry·G M RealmutoL M Greenberg
Dec 1, 1980·The Australian and New Zealand Journal of Psychiatry·G F Johnson
Mar 2, 2005·Journal of Clinical Psychopharmacology·Mario Rodrigues Louzã, Debora Pastore Bassitt

Citations

Jan 1, 1997·Journal of Neural Transmission·E SchulzH Remschmidt
Jan 5, 2001·European Child & Adolescent Psychiatry·C Gillberg
Oct 28, 1998·Journal of Psychiatric Research·C FleischhakerH Remschmidt
May 15, 2004·Journal of Child and Adolescent Psychopharmacology·Deanna L KellyRobert R Conley
Jan 15, 2005·Journal of Child and Adolescent Psychopharmacology·Jennifer Cheng-ShannonJames T McCracken
Jan 1, 1993·Journal of the American Academy of Child and Adolescent Psychiatry·B Blanz, M H Schmidt
Jan 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·T MozesA Weizman
Mar 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·Y LevkovitchB Gaoni
Jun 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·K E TowbinR G Pugliese
Jul 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·K McKennaJ L Rapoport
Nov 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·D C Fuchs
Feb 1, 1995·Journal of the American Academy of Child and Adolescent Psychiatry·M S BurkeS Schulman
Mar 1, 1995·Journal of the American Academy of Child and Adolescent Psychiatry·Y LevkovitchB Gaoni
Nov 1, 1995·Journal of the American Academy of Child and Adolescent Psychiatry·A AdinamisW Kronenberger
Jul 1, 1996·Journal of the American Academy of Child and Adolescent Psychiatry·F R Volkmar
May 1, 1997·Journal of the American Academy of Child and Adolescent Psychiatry·J L ArmenterosJ Gorman
Apr 7, 2007·Journal of Psychiatric Practice·H QuintanaDon Mercante
Aug 18, 2000·Paediatric Drugs·H RemschmidtE Schulz
Feb 12, 1998·Journal of the American Academy of Child and Adolescent Psychiatry·J McClellan, J Werry
Oct 1, 1995·Journal of the American Academy of Child and Adolescent Psychiatry·H Quintana, M Keshavan
Nov 24, 2004·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Paz TorenA Weizman
Jun 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·L K JacobsenJ L Woolston
Jun 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·J A FrazierJ L Rapoport
Mar 16, 2001·Expert Opinion on Pharmacotherapy·R L FindlingB L Gracious
Jun 1, 1997·The British Journal of Psychiatry : the Journal of Mental Science·M TuretzA Weizman
Mar 1, 1996·The British Journal of Psychiatry : the Journal of Mental Science·T H MacEwan, M J Morton
Mar 1, 1995·The British Journal of Psychiatry : the Journal of Mental Science·C A Kaplan, S Hussain
Jan 23, 2009·The Cochrane Database of Systematic Reviews·Adib EssaliJohn Rathbone

Related Concepts

Leponex
Factor Construct Rating Scales (Fcrs)
Schizophrenia
Schizophrenic Psychology

Related Feeds

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here

Related Papers

Journal of the American Academy of Child and Adolescent Psychiatry
T MozesA Weizman
Journal of the American Academy of Child and Adolescent Psychiatry
R S Diler, A Avci
Journal of the American Academy of Child and Adolescent Psychiatry
M CampbellG M Simpson
© 2021 Meta ULC. All rights reserved