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CLU rs11136000 promotes early cognitive decline in Parkinson's disease

Movement Disorders : Official Journal of the Movement Disorder Society

Jan 14, 2020

Frederic SampedroJaime Kulisevsky

Abstract

The C allele of the rs11136000 genetic variant of the clusterin gene has been associated with increased risk of Alzheimer's disease. However, a comprehensive characterization of the role of this genetic variant in early cognitive deterioration in PD is lacking. Using the Parkinson's Pro...read more

Mentioned in this Paper

Movement Disorders
Posterior Part of Thigh
Frontal Lobe
Mild Cognitive Disorder
Progressive Disease
Dementia
Diagnosis
Neurodegenerative Disorders
Therapy Naive
Memory
5
1
Paper Details
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CLU rs11136000 promotes early cognitive decline in Parkinson's disease

Movement Disorders : Official Journal of the Movement Disorder Society

Jan 14, 2020

Frederic SampedroJaime Kulisevsky

PMID: 31930747

DOI: 10.1002/mds.27949

Abstract

The C allele of the rs11136000 genetic variant of the clusterin gene has been associated with increased risk of Alzheimer's disease. However, a comprehensive characterization of the role of this genetic variant in early cognitive deterioration in PD is lacking. Using the Parkinson's Pro...read more

Mentioned in this Paper

Movement Disorders
Posterior Part of Thigh
Frontal Lobe
Mild Cognitive Disorder
Progressive Disease
Dementia
Diagnosis
Neurodegenerative Disorders
Therapy Naive
Memory
5
1

Similar Papers Found In These Feeds

Gut Microbiota in Movement Disorders

Gut microbiota has been implicated in neurodevelopment, neuroinflammatory responses, and neurological disorders. Here is the latest research on the role of gut microbiota in movement disorders.

Frontotemporal Dementia

Frontotemporal dementia (FTD) refers to disorders caused by progressive neuronal loss in the frontal and temporal lobes of the brain. Here is the latest research on FTD and FTD-associated disorders.

Related Papers

Movement Disorders : Official Journal of the Movement Disorder Society

Cognitive executive impairment and dopaminergic deficits in de novo Parkinson's disease

Movement Disorders : Official Journal of the Movement Disorder SocietyOctober 7, 2014
Françoise J SiepelDag Aarsland
Paper Details
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