PMID: 46690Mar 1, 1975

Clues to cancer risk: biologic markers

American Family Physician
H T LynchJ F Lynch

Abstract

Two large kindreds manifesting the "cancer family syndrome" have been studied. Genetic and biologic studies reveal markers which have important implications for cancer detection, control and prevention. Valuable markers may be found in the major histocompatibility system, HL-A. The presence of carcinoembryonic antigen and SV-40 viral transformation of skin fibroblasts are other possibly important markers. Relationships of the ABO blood groups to cancer are under intensive study, as is the hepatitis-associated antigen.

Related Concepts

Hepatitis B Antigens
Blood Group H Type 1 Antigen
Simian virus 40
Fetal Proteins
Carcinoembryonic Antigen
HLA Antigens
Culture Techniques
Hereditary Non-Polyposis Colon Cancer Type 2
Malignant Neoplasm of Gastrointestinal Tract
Fibroblasts

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