Cluster analysis and lower urinary tract symptoms in men: findings from the Boston Area Community Health Survey

BJU International
Amy CinarRaymond C Rosen

Abstract

To classify lower urinary tract symptoms (LUTS) in a large, representative sample of men in the USA by means of cluster analysis and to investigate risk factors and comorbidities associated with the resulting cluster patterns. A combination of hierarchical and non-hierarchical cluster methods was used to assign men with LUTS in the Boston Area Community Health (BACH) study to symptom-based categories or clusters. Of the 2301 men in the BACH study, those reporting one or more of 14 common LUTS (1592 men) were included in the analysis. The prevalence and frequency of symptoms in each cluster was assessed, in addition to the demographic, lifestyle risk factors, comorbidities, quality of life, and interference with activities of daily living associated with each cluster. We used anova methods for assessing cluster effects on continuous variables, and cross-classification and chi-square tests for categorical measures. Internal validity of the cluster solution was tested by means of a split-half replication, and external validity by comparison with previously published data. Five clusters were identified among symptomatic men. About half of the symptomatic men were assigned to Cluster 1, which included individuals with a low prevalen...Continue Reading

References

Dec 1, 1992·Journal of Clinical Epidemiology·R S EpsteinD Patrick
Apr 9, 1994·BMJ : British Medical Journal·P Abrams
Feb 1, 1993·Journal of Clinical Epidemiology·R A WashburnC A Janney
May 1, 1997·Urology·M P O'LearyJ Spolarich-Kroll
Jun 1, 2001·Neurourology and Urodynamics·T KnutsonC Dahlstrand
Apr 20, 2004·Current Opinion in Urology·Saurabh BhargavaChristopher R Chapple
Nov 2, 2004·Statistical Methods in Medical Research·Brian Everitt
Feb 1, 2005·BJU International·Christopher R Chapple, Alan J Wein
Jan 28, 2006·Forensic Science International : Synergy·Hilda Clotilde Penteado MoranaJulio Arboleda-Flórez
Oct 14, 2006·Emergency Radiology·Dan BrisonStephen R Baker
Oct 9, 2007·Urology·Heather J LitmanUNKNOWN Boston Area Community Health Survey Investigators
Mar 14, 2008·BJU International·Karin S CoyneIan Milsom

❮ Previous
Next ❯

Citations

Dec 12, 2012·International Journal of Epidemiology·Rebecca S PiccoloJohn B McKinlay
Aug 25, 2009·European Urology·Roger Dmochowski
Oct 1, 2013·International Journal of Clinical Practice·K S CoyneI Milsom
Aug 26, 2010·Journal of Advanced Nursing·Emily A ElstadSharon L Tennstedt
May 2, 2009·European Urology·Christopher R Chapple
Jun 13, 2017·Current Opinion in Urology·Omar Al Hussein AlawamlhRichard K Lee

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.