Clustering Analysis of Antibiograms and Antibiogram Types of Streptococcus agalactiae Strains from Tilapia in China

Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease
Chan LiuYoulu Su

Abstract

In view of the changing antibiotic-resistance profiles of Streptococcus agalactiae from tilapia in China, antimicrobial susceptibilities of 75 S. agalactiae strains were determined by the disc diffusion method, and cluster analyses of the antibiograms and antibiogram types were performed. All strains displayed multidrug resistance (MDR). The antimicrobial-resistance rates were highest (>90%) to aminoglycosides, sulfonamides, pipemidic acid, and norfloxacin, followed by penicillin, ampicillin, and ciprofloxacin (26.7-38.7%); those to furadantin, lincomycin, erythromycin, ofloxacin, tetracycline, and florfenicol were low (<10%), and no resistance to vancomycin, cefalexin, cefoxitin, amoxicillin, medemycin, doxitard, oxytetracycline, rifampin, chloramphenicol, or thiamphenicol was detected. Statistical analysis showed that the resistance rate to ciprofloxacin increased significantly in 2016 (p = 0.009), whereas that to trimethoprim/sulfamethoxazole decreased (p = 0.017). Cluster analyses identified that the strains had 23 antibiogram types (A-W) and clustered in five groups (Groups I-V). The strains with higher antimicrobial resistance mainly clustered in Groups I and II. Our results show that the antibiograms varied with time and...Continue Reading

References

Mar 10, 2005·Basic & Clinical Pharmacology & Toxicology·Frank M Aarestrup
Mar 28, 2006·The Journal of Antimicrobial Chemotherapy·Alberto SandiumengeJordi Rello
May 14, 2008·The Journal of Antimicrobial Chemotherapy·UNKNOWN Lord Soulsby of Swaffham Prior
Jul 29, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A-P MagiorakosD L Monnet
Jun 13, 2014·BMC Infectious Diseases·Vanusa G DutraSérgio Eduardo L Fracalanzza
Feb 3, 2015·Frontiers in Microbiology·Daniel E Carey, Patrick J McNamara
Mar 19, 2015·Foodborne Pathogens and Disease·Łukasz MąkaMagdalena Popowska
Dec 22, 2016·Diseases of Aquatic Organisms·Guangjin LiuChengping Lu
Feb 10, 2017·Frontiers in Microbiology·Satoru SuzukiTong Zhang

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.