Clustering of cardiovascular risk factors in association with indices of adiposity and adipose tissue distribution in adults

American Journal of Human Biology : the Official Journal of the Human Biology Council
R N BaumgartnerA F Roche

Abstract

The hypothesis, that clustering of elevated levels of blood pressures, plasma lipids and lipoprotein cholesterols, and serum glucose in men and women was associated with indices of adiposity and adipose tissue distributione was tested while controlling for family membership, age, level of education, income, and smoking as well as menopause (surgical and natural )and the use of oral contraceptives and replacement estrogens in women. The study population included 146 white men and 171 white women, 18-88 years of age, from 4 large kindreds residing in the Dayton, Ohio, metropolitan area. The data were collected between 1977 and 1980 as part of a study of genetic factors in essentials hypertension. Four groups of individuals with similar levels for blood pressures, plasma lipids and lipoprotein cholesterols, and serum glucose were defined for each sex by using a k-means clustering algorithm. A group was identified in each sex that had higher than average values for all of these risk factors. Membership in this group was associated significantly with age and weight/stature(2) in the men, and with age, weight/stature(2) and the interaction of age and weight/stature(2) in the women, after controlling for level of education, income, sm...Continue Reading

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Citations

Jul 20, 2017·The British Journal of Nutrition·Anna RiedlJakob Linseisen
Jan 1, 1998·American Journal of Human Biology : the Official Journal of the Human Biology Council·B Nirmala Reddy
Feb 23, 2010·Suicide & Life-threatening Behavior·Heather Booth

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