Clustering of slowly adapting type II mechanoreceptors in human peripheral nerve and skin

Brain : a Journal of Neurology
G WuR G Hallin

Abstract

The intrafascicular organization of human peripheral nerves was studied with percutaneous microneurography in the median, radial and peroneal nerves with one-surface or two-surface thin diameter concentric needle electrodes. Data from 33 recording sites containing 47 slowly adapting type II (SAII) units were analysed. At many sites two, sometimes even three, neighbouring SAII units were recorded from the explored nerve fascicle and they had adjacent or even overlapping cutaneous receptive fields. Among pairs of SAII units found at the same site, one unit often had ongoing discharge, whereas the other was silent under resting conditions. The neighbouring SAII units were optimally activated by stretching the skin in different directions. Stretching the same skin area in different directions produced different unit recruitment. Clustered SAII units were often found in sites where Pacinian afferents and skin sympathetic activity were also recorded. No significant difference was observed in the degree of grouping of SAII units either between recordings obtained with one-surface versus two-surface electrodes or between glabrous and hairy skin. The data do not support the notion that myelinated fibres are randomly organized in periphe...Continue Reading

Citations

Oct 3, 2002·Behavioural Brain Research·R G HallinG Wu
Apr 27, 2000·Cellular Signalling·Y Chern
Sep 10, 2005·International Journal of Obesity : Journal of the International Association for the Study of Obesity·K MalmlöfK Rimvall
Oct 2, 2013·Journal of Motor Behavior·Jacqlyn KingAndrew Karduna
Apr 20, 2004·Neuroreport·Bettina PollokWolfgang Prinz
Sep 27, 2006·Neuroreport·Susan KoenekeLutz Jäncke
Sep 28, 2002·Anesthesia and Analgesia·Tadanobu YasudaAkitomo Matsuki
May 16, 2013·Journal of Athletic Training·Alan R NeedleThomas W Kaminski
Nov 22, 2001·Experimental Neurology·R G Hallin, G Wu
Oct 16, 2015·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Shaoyu QiaoKen Yoshida
Apr 5, 2005·The Journal of Bone and Joint Surgery. American Volume·Wei-Chun LiJau-Yih Tsauo
Nov 25, 2020·Nature Biomedical Engineering·Sliman J BensmaiaSilvestro Micera

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