CMV reactivation induced BK virus-associated late onset hemorrhagic cystitis after peripheral blood stem cell transplantation

Bone Marrow Transplantation
B BieloraiA Toren

Abstract

Hemorrhagic cystitis (HC) is a known complication of stem cell transplantation. In contrast to early-onset HC that is usually attributed to cyclophosphamide and occurs within a few days of infusion, late onset HC is associated with viral infection. In recent years BK virus has emerged as an important causative agent. We describe two patients who developed late onset HC (38 and 92 days post transplant) associated with BK viruria concomitant with CMV reactivation and suggest a possible role of CMV in the process of BK virus DNA replication.

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Citations

Jun 4, 2008·Current Urology Reports·Darius A Paduch
Jul 24, 2008·Bone Marrow Transplantation·E CastagnolaR Haupt
Mar 3, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ritambhra NadaKusum Joshi
Aug 19, 2006·Critical Care Medicine·Ayman O Soubani
Jun 20, 2014·Current Infectious Disease Reports·Jennifer delaCruz, Kenneth Pursell
Aug 8, 2009·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Peter H O'DonnellKoen van Besien
Sep 30, 2016·World Journal of Transplantation·Darlene VigilAntonios H Tzamaloukas
Jul 26, 2005·Transplantation·Mieko ToyodaStanley C Jordan
Apr 30, 2003·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Ludwig PatzerJoachim Misselwitz
Jan 1, 2007·Current Prostate Reports·Darius A Paduch
Mar 23, 2021·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Isabel Rodríguez-GoncerMario Fernández-Ruiz

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