CNS disease triggering Takotsubo stress cardiomyopathy

International Journal of Cardiology
Josef Finsterer, Karim Wahbi


There are a number of hereditary and non-hereditary central nervous system (CNS) disorders, which directly or indirectly affect the heart (brain-heart disorders). The most well-known of these CNS disorders are epilepsy, stroke, infectious or immunological encephalitis/meningitis, migraine, and traumatic brain injury. In addition, a number of hereditary and non-hereditary neurodegenerative disorders may impair cardiac functions. Affection of the heart may manifest not only as arrhythmias, myocardial infarction, autonomic impairment, systolic dysfunction/heart failure, arterial hypertension, or pulmonary hypertension, but also as stress cardiomyopathy (Takotsubo syndrome, TTS). CNS disease triggering TTS includes subarachnoid bleeding, epilepsy, ischemic stroke, intracerebral bleeding, migraine, encephalitis, traumatic brain injury, PRES syndrome, or ALS. Usually, TTS is acutely precipitated by stress triggered by various different events. TTS is one of the cardiac abnormalities most frequently induced by CNS disorders. Appropriate management of TTS from CNS disorders is essential to improve the outcome of affected patients.


Feb 1, 1997·International Journal of Cardiology·T D WangY T Lee
Feb 7, 2001·Stroke; a Journal of Cerebral Circulation·S NarediP Friberg
Mar 15, 2001·Surgical Neurology·J W Donaldson, M B Pritz
Jul 14, 2001·Journal of the American College of Cardiology·K TsuchihashiUNKNOWN Angina Pectoris-Myocardial Infarction Investigations in Japan
Aug 9, 2001·The European Respiratory Journal·S M Studer, P B Terry
Oct 27, 2004·Circulation Journal : Official Journal of the Japanese Circulation Society·Norihito SasakiChiaki Shigemasa
Jan 14, 2005·Internal Medicine·Masahiro OomuraKoji Shigeno
Mar 18, 2005·Heart and Vessels·Kenya SakaiToshio Nakanishi
Jun 16, 2005·Neurology·Peter S ChinKyra J Becker
Aug 3, 2006·Clinical Cardiology·Simona Parvulescu-CodreaAllan S Jaffe
Sep 5, 2006·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Stephanie A Mitchell, Richard A Crone
Oct 20, 2006·International Journal of Cardiology·Matthew I Worthley, Todd J Anderson
Nov 16, 2006·Internal Medicine·Yasutaka Tajima, Akihisa Matsumoto
Mar 14, 2007·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·S G WeeksR B Bell
Nov 30, 2007·Congestive Heart Failure·Surya M ArthamJ Stephen Jenkins
Dec 28, 2007·International Journal of Cardiology·Tsung O Cheng
Mar 22, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M E BoscaJ Ruvira
Apr 10, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S-C SeowC-H Lee
Apr 12, 2008·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Sylvestre MaréchauxPierre-Vladimir Ennezat
Apr 24, 2008·Clinical Cardiology·Ali R RahimiJacob Mills
Apr 30, 2008·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Hendrik BonnemeierChristof Burgdorf
May 6, 2008·Rinshō shinkeigaku = Clinical neurology·Yumi MatsuyamaJun-ichi Kira
May 24, 2008·International Journal of Cardiology·Satoshi KurisuHiroki Ikenaga
May 29, 2008·Neurocritical Care·Stephane LegrielJean Pierre Bedos
Aug 9, 2008·Annals of Neurology·Sohei YoshimuraKazuo Minematsu
Dec 10, 2008·The Journal of Trauma·Maria RieraCarmen Blanco
Feb 25, 2009·International Journal of Cardiology·Kyoko WakabayashiHiroyuki Daida
Mar 10, 2009·Journal of Neurology·Yuji KatoNorio Tanahashi
Mar 10, 2009·Cardiology·Vasco DiasSevero Torres
Mar 14, 2009·La Presse médicale·Patrick SchianoJacques Monségu
Mar 26, 2009·Coronary Artery Disease·Satoshi KurisuHiroki Ikenaga

❮ Previous
Next ❯


Dec 3, 2014·International Journal of Cardiology·Josef Finsterer, Claudia Stöllberger
Jan 25, 2016·International Journal of Cardiology·P Stefan BiesbroekRamon B van Loon
Sep 13, 2015·Seizure : the Journal of the British Epilepsy Association·Josef Finsterer, Anna Bersano
Nov 19, 2015·International Journal of Cardiology·Josef Finsterer, Claudia Stöllberger
Oct 12, 2015·Seizure : the Journal of the British Epilepsy Association·Josef Finsterer, Anna Bersano
Jul 6, 2015·International Journal of Cardiology·Josef Finsterer, Anna Bersano
Aug 25, 2015·International Journal of Cardiology·Giacomo MugnaiCorrado Vassanelli
Jun 22, 2016·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Eugene A Hessel
Aug 16, 2016·International Journal of Cardiology·Josef Finsterer, Claudia Stöllberger
Sep 18, 2016·Heart Failure Clinics·Ilan S Wittstein
Apr 25, 2017·Annals of Neurology·Géraldine AndrodiasSandra Vukusic
Dec 21, 2017·Neurocritical Care·Kevin T GobeskeEelco F Wijdicks
Jun 14, 2017·Circulation·Francesco PellicciaPaolo G Camici
Sep 29, 2018·Journal of Neurotrauma·You-Jing JiangLin Zhang
Jul 16, 2017·BMJ Case Reports·Jithin SajeevGary Gordon
Feb 20, 2018·BMJ Case Reports·Maria MenezesCatarina Salvado
Sep 7, 2019·Herzschrittmachertherapie & Elektrophysiologie·Theodor W May, Carsten W Israel
Aug 19, 2015·Current Opinion in Anaesthesiology·Dhuleep S WijayatilakeSuyogi V Jigajinni
Jul 18, 2020·The International Journal of Neuroscience·Adam Ranellone, Michael G Abraham
Sep 6, 2019·Herzschrittmachertherapie & Elektrophysiologie·Malte Meesmann
Sep 24, 2020·ESC Heart Failure·Masaki TsujiIssei Komuro
May 28, 2019·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Josef Finsterer
Mar 24, 2018·Current Neurology and Neuroscience Reports·M RanieriA Bersano
Oct 14, 2018·Medicine·Simona PortaroRocco Salvatore Calabrò
Aug 11, 2018·Neurocritical Care·Nicholas A MorrisHooman Kamel
May 27, 2020·Journal of Clinical Neuromuscular Disease·Matthew KatzPamela McCombe
Dec 22, 2016·Neurocritical Care·Chun Fai CheahRaimund Helbok
Sep 17, 2017·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Shams Y-Hassan, Per Tornvall
Jul 31, 2018·Heart Failure Reviews·Sonia BorodziczAgnieszka Cudnoch-Jędrzejewska
Jun 15, 2017·Neurocritical Care·Deena M NasrAlejandro A Rabinstein
Apr 3, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Manuel RattkaMirjam Keßler
Mar 11, 2017·Internal and Emergency Medicine·Josef Finsterer, Claudia Stöllberger
May 21, 2019·Journal of Medical Case Reports·A GravosA Prekates
Feb 13, 2021·BMC Cardiovascular Disorders·Yuki KakinumaRyuta Kinno
Oct 29, 2020·Curēus·Juliette ConteNeil P Larson
Mar 10, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Amado Jimenez-RuizLuciano A Sposato
Feb 24, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Junji KoyamaAtsufumi Kawamura
Apr 7, 2021·Journal of Cardiac Surgery·Josef Finsterer
Jul 17, 2021·Current Atherosclerosis Reports·Victoria L CammannChristian Templin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Amyloid Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS) is a progressive nervous system disease associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS here.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.


Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.


Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

Related Papers

Journal of the Neurological Sciences
Josef Finsterer, Karim Wahbi
Perspective infirmière : revue officielle de l'Ordre des infirmières et infirmiers du Québec
Daniel Milhomme
Cephalalgia : an International Journal of Headache
Johann GroßkopfJosef G Heckmann
© 2021 Meta ULC. All rights reserved