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CNVeM: copy number variation detection using uncertainty of read mapping

Journal of Computational Biology : a Journal of Computational Molecular Cell Biology

Feb 21, 2013

Zhanyong WangEleazar Eskin

Abstract

Copy number variations (CNVs) are widely known to be an important mediator for diseases and traits. The development of high-throughput sequencing (HTS) technologies has provided great opportunities to identify CNV regions in mammalian genomes. In a typical experiment, millions of short ...read more

Mentioned in this Paper

In Silico
DNA Copy Number Changes
Genome
Uncertainty
Sequencing
Mediator of activation protein
Nucleotides
High-Throughput Nucleotide Sequencing
Two-Parameter Models
Chromosomes, Mammalian
7
54
Paper Details
References
  • References22
  • Citations9
123
  • References22
  • Citations9
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Copy Number Variation

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CNVeM: copy number variation detection using uncertainty of read mapping

Journal of Computational Biology : a Journal of Computational Molecular Cell Biology

Feb 21, 2013

Zhanyong WangEleazar Eskin

PMID: 23421794

DOI: 10.1089/cmb.2012.0258

Abstract

Copy number variations (CNVs) are widely known to be an important mediator for diseases and traits. The development of high-throughput sequencing (HTS) technologies has provided great opportunities to identify CNV regions in mammalian genomes. In a typical experiment, millions of short ...read more

Mentioned in this Paper

In Silico
DNA Copy Number Changes
Genome
Uncertainty
Sequencing
Mediator of activation protein
Nucleotides
High-Throughput Nucleotide Sequencing
Two-Parameter Models
Chromosomes, Mammalian
7
54

Similar Papers Found In These Feeds

Copy Number Variation

Copy number variation refers to alterations in the number of gene copies or DNA sequences. It can be a duplication, amplification, or a deletion event. Here is the latest research.

Related Papers

Nucleic Acids Research

Detecting common copy number variants in high-throughput sequencing data by using JointSLM algorithm

Nucleic Acids ResearchFebruary 16, 2011
Alberto MagiFrancesca Torricelli
Paper Details
References
  • References22
  • Citations9
123
  • References22
  • Citations9
1
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