PMID: 9421125Jan 8, 1998Paper

Co-existing gastric cancer and duodenal ulcer disease: role of Helicobacter pylori infection

Helicobacter
H Y KimD Y Graham

Abstract

The association of gastric cancer and chronic duodenal ulcer disease is considered rare. In fact duodenal ulcer disease is believed to somehow "protect" against the development of gastric cancer. Helicobacter pylori infection is an important factor in the development of gastric cancer. No detailed investigation on the prevalence of H. pylori in coexistence of gastric cancer and duodenal ulcer disease has been performed. We evaluated the frequency of H. pylori infection in the patients with co-existence of gastric cancer and duodenal ulcer disease. During the period March 1994 to February 1995, we collected data from 3,652 patients in whom esophagogastroduodenoscopy was done. During this period, when the cancerous or ulcerative lesions in stomach or duodenum were found, rapid urease tests were performed. Six patients had concurrent gastric carcinoma and duodenal ulcer disease. Three of the cases had early gastric carcinoma; 2 had active duodenal ulcers and one had a duodenal ulcer scar; all 3 had positive rapid urease tests. The patients with early gastric cancer were younger than the individuals with advanced gastric cancer. The co-existence of both diseases may be higher than reported from Western countries or from Peru which ...Continue Reading

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Citations

Jan 6, 2009·Current Opinion in Gastroenterology·Hala El-Zimaity
May 17, 2014·World Journal of Gastroenterology : WJG·David Y Graham
Sep 24, 2005·International Journal of Clinical Practice·L ZhaoJ-P Yu
Nov 16, 2010·Helicobacter·Soo-Jeong ChoYoung-Woo Kim
Jul 23, 2003·The American Journal of Gastroenterology·David Y Graham
Mar 31, 2001·The American Journal of Gastroenterology· El-Zimaity HMTD Y Graham
Jun 18, 2009·World Journal of Gastroenterology : WJG·Kate L MandevilleShahid A Khan
Mar 29, 2014·The Tohoku Journal of Experimental Medicine·Hirohiko ShinkaiTooru Shimosegawa
Sep 29, 2006·World Journal of Gastroenterology : WJG·Hala M T El-Zimaity

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