Co-Infection of Swine with Porcine Circovirus Type 2 and Other Swine Viruses

Viruses
Ting OuyangLinzhu Ren

Abstract

Porcine circovirus 2 (PCV2) is the etiological agent that causes porcine circovirus diseases and porcine circovirus-associated diseases (PCVD/PCVAD), which are present in every major swine-producing country in the world. PCV2 infections may downregulate the host immune system and enhance the infection and replication of other pathogens. However, the exact mechanisms of PCVD/PCVAD are currently unknown. To date, many studies have reported that several cofactors, such as other swine viruses or bacteria, vaccination failure, and stress or crowding, in combination with PCV2, lead to PCVD/PCVAD. Among these cofactors, co-infection of PCV2 with other viruses, such as porcine reproductive and respiratory syndrome virus, porcine parvovirus, swine influenza virus and classical swine fever virus have been widely studied for decades. In this review, we focus on the current state of knowledge regarding swine co-infection with different PCV2 genotypes or strains, as well as with PCV2 and other swine viruses.

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Citations

Jul 25, 2020·Translational Animal Science·Jordan T GebhardtSteve C Henry
Oct 28, 2020·Transboundary and Emerging Diseases·Maria Soledad SerenaMaria Gabriela Echeverría
Jan 2, 2021·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Izabel C V P GogoneFlavia R O de Barros
Jun 22, 2021·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Tamara StäubliJulia Lechmann
Jul 6, 2021·Frontiers in Veterinary Science·Xiangqi HaoShoujun Li
Jul 27, 2021·Transboundary and Emerging Diseases·Viviane Sisdelli AssaoAbelardo Silva-Júnior

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