Co-production of polyhydroxyalkanoates and carotenoids through bioconversion of glycerol by Paracoccus sp. strain LL1

International Journal of Biological Macromolecules
Prasun KumarBeom Soo Kim

Abstract

Polyhydroxyalkanoates (PHA) have emerged as a potential alternative to synthetic plastics, although its large-scale production is limited by the expenditure incurred in feed materials. Co-production of various valuable bioproducts along with PHA has been proposed to alleviate the overall production cost. Here, high-yield co-production of PHA and carotenoids was achieved in single step fermentation by Paracoccus sp. LL1. The halophilic bacterial strain could metabolize a wide range of substrates including methanol, lactose, galactose, glycerol, fructose, mannitol, etc. Under batch fermentation using mineral media supplemented with 2% glycerol, Paracoccus sp. LL1 synthesized 3.77gL-1 PHA with concomitant production of 3.6mgL-1 of carotenoids after 96h. An enhancement of 2.2-folds in total dry cell weight (DCW) was achieved through cell retention culture of Paracoccus sp. LL1, resulting in a maximum DCW (24.2gL-1) containing PHA (39.3%, ww-1) with concomitant enhancement in the production of total carotenoids. Paracoccus sp. LL1 could convert glycerol into carotenoids and PHA to a level of 7.14mgL-1 and 9.52gL-1, respectively. It is the first report showing value addition in PHA production process through co-production of high val...Continue Reading

Citations

Dec 21, 2018·Biotechnology and Applied Biochemistry·Prasun KumarBeom Soo Kim
Oct 28, 2018·Applied Microbiology and Biotechnology·Tatiana VolovaNatalia Zhila
Apr 10, 2019·Polymers·Valeria MezzollaPalmiro Poltronieri
Jan 21, 2019·Bioprocess and Biosystems Engineering·Ezhaveni SathiyamoorthiBeom Soo Kim
Feb 2, 2019·Applied Biochemistry and Biotechnology·Maria J MotaJorge A Saraiva
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Dattatray K BedadeRichard A Gross
Oct 15, 2021·Environmental Science and Pollution Research International·Lijun ShenGuang Chen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Water Science and Technology : a Journal of the International Association on Water Pollution Research
Hiroo TakabatakeT Matsuo
Microbial Biotechnology
Chad NielsenCharles D Miller
© 2022 Meta ULC. All rights reserved