CO2 transport in agnathan blood: evidence of erythrocyte Cl-/HCO3- exchange limitations

Respiration Physiology
B L Tufts, R G Boutilier

Abstract

CO2 transport properties of blood were examined in the lamprey Petromyzon marinus and the hagfish Myxine glutinosa. In order to evaluate possible chloride/bicarbonate exchange limitations, experiments were conducted under control conditions and in the presence of an ionophore to permit equilibrium distribution of chloride, bicarbonate, and protons across the erythrocyte membrane. The ionophore, tri-n-propyl tin chloride, markedly altered the CO2 transport properties and apparent nonbicarbonate buffering characteristics of the blood of Petromyzon marinus. In addition, the distributions of protons, bicarbonate and chloride ions across the erythrocyte membrane were very different from each other under control conditions, but became very similar in the presence of the anionic ionophore. The CO2 transport properties of the blood of Myxine glutinosa were not significantly different in the presence of the ionophore. Small but significant changes were observed, however, in erythrocyte pH, chloride concentration and water content in the presence of tri-n-propyl tin chloride. These results demonstrate that chloride/bicarbonate exchange limitations and possibly active transport of protons contribute to the unique CO2 transport properties ...Continue Reading

References

Sep 1, 1977·The Journal of General Physiology·R Zeidler, H D Kim
Jul 1, 1977·The Journal of Clinical Investigation·R A CooperM H Leslie
Oct 1, 1977·The Journal of Membrane Biology·K F Schnell
May 12, 1987·Biochimica Et Biophysica Acta·M Nikinmaa, E Railo
Aug 1, 1985·Respiration Physiology·R G BoutilierD J Randall
Aug 1, 1985·Respiration Physiology·C Albers, K G Goetz

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Citations

Jan 1, 1996·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·B A CameronB L Tufts
Mar 16, 2001·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·B L TuftsS Currie
May 9, 2006·Respiratory Physiology & Neurobiology·A J Esbaugh, B L Tufts
May 12, 2009·Respiratory Physiology & Neurobiology·Andrew J EsbaughS F Perry
Mar 8, 2003·The Journal of Experimental Biology·Gabriele MüllerRoy E Weber
Apr 1, 1996·International Journal of Pancreatology : Official Journal of the International Association of Pancreatology·X WangI Ihse

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