Coagulation and ablation patterns of high-intensity focused ultrasound on a tissue-mimicking phantom and cadaveric skin

Lasers in Medical Science
Hee-Jin KimSung Bin Cho

Abstract

High-intensity focused ultrasound (HIFU) can be applied noninvasively to create focused zones of tissue coagulation on various skin layers. We performed a comparative study of HIFU, evaluating patterns of focused tissue coagulation and ablation upon application thereof. A tissue-mimicking (TM) phantom was prepared with bovine serum albumin and polyacrylamide hydrogel to evaluate the geometric patterns of HIFU-induced thermal injury zones (TIZs) for five different HIFU devices. Additionally, for each device, we investigated histologic patterns of HIFU-induced coagulation and ablation in serial sections of cadaveric skin of the face and neck. All HIFU devices generated remarkable TIZs in the TM phantom, with different geometric values of coagulation for each device. Most of the TIZs seemed to be separated into two or more tiny parts. In cadaveric skin, characteristic patterns of HIFU-induced ablation and coagulation were noted along the mid to lower dermis at the focal penetration depth of 3 mm and along subcutaneous fat to the superficial musculoaponeurotic system or the platysma muscle of the neck at 4.5 mm. Additionally, remarkable pre-focal areas of tissue coagulation were observed in the upper and mid dermis at the focal pen...Continue Reading

References

Jun 1, 1970·The Journal of the Acoustical Society of America·J B Pond
Jun 1, 1984·International Journal of Radiation Oncology, Biology, Physics·S A Sapareto, W C Dewey
Jan 1, 1993·European Urology·G R ter Haar, D Robertson
May 15, 2003·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·M W DewhirstP J Hoopes
Jun 21, 2007·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Gail Ter Haar, Constantin Coussios
Feb 29, 2008·Lasers in Surgery and Medicine·W Matthew WhiteRichard Gliklich
Apr 24, 2008·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Hans J LaubachDieter Manstein
Oct 30, 2010·Ultrasound in Medicine & Biology·Adam D MaxwellCharles A Cain
Feb 25, 2014·Nature Reviews. Cancer·Katrina F Chu, Damian E Dupuy
Oct 8, 2014·Plastic and Reconstructive Surgery. Global Open·Daniele BaniGiulia Lo Russo

❮ Previous
Next ❯

Citations

Jul 20, 2016·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·S B ChoB J Kim
Aug 12, 2016·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·T-R KwonB J Kim
Sep 7, 2016·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Dong Hye SuhHei Sung Kim
Sep 14, 2017·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Heedae JeonSung Bin Cho
Nov 22, 2016·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·K J AhnS B Cho
Nov 22, 2016·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·J-H ParkU C Yeo
Oct 16, 2018·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Heesu KimSung Bin Cho
Jun 28, 2019·Biomedical Engineering Online·Suhyun ParkHyun Wook Kang
May 6, 2019·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Sung Bin ChoKwang Ho Yoo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Related Papers

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
Xin ZhangLian Zhang
© 2021 Meta ULC. All rights reserved