PMID: 8976347Dec 1, 1996Paper

Coagulation changes during thoracoabdominal aneurysm repair

Journal of Vascular Surgery
J P GertlerW M Abbott

Abstract

The cause of coagulopathic hemorrhage during thoracoabdominal aneurysm (TAA) repair has not been well defined in human studies. We investigated changes in the coagulation system associated with supraceliac versus infrarenal cross-clamping to address this critical issue. Blood levels of fibrinogen, the prothrombin fragment F1.2, D-dimer, and factors II, V, VII, VIII, IX, X, XI, and XII were analyzed in 19 patients with TAAs and four patients with abdominal aortic aneurysms (AAAs) at: (A) induction; (B) 30 minutes into supraceliac (TAA) or infrarenal (AAA) clamping; (C) 30 minutes after release of supraceliac or infrarenal clamps; and (D) immediately after surgery. Preoperative and intraoperative variables, including but not limited to aneurysm type, pathologic findings, comorbid conditions, clamp times, volume and timing of blood products, and clinical outcome, were prospectively recorded. Significance was determined by analysis of variance, Student's t test, and univariate linear regression. Levels of fibrinogen and factors II, V, VIII, VIII, IX, X, XI, and XII decreased (p < 0.05) at time B versus time A and returned to near baseline by time D. D-dimer and F1.2 increased starting at time B and reached significance (p < 0.05) b...Continue Reading

References

Jun 1, 1991·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·P D Micallef-Eynaud, C A Ludlam
May 1, 1989·Archives of Surgery·R P CambriaW M Abbott
May 1, 1994·American Journal of Surgery·M T Janusz

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Citations

Jun 17, 1999·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·K MorishitaT Abe
Jan 31, 2012·The Journal of Thoracic and Cardiovascular Surgery·Deniz GoksedefKonstadinos A Plestis
Oct 1, 2011·Journal of Cardiothoracic and Vascular Anesthesia·Gary A MorrisonAlastair F Nimmo
Feb 21, 2006·The Annals of Thoracic Surgery·Paul W G ElbersMisa Dzoljic
Nov 4, 2011·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Jinyoung HwangSunghee Han
May 23, 2001·The Journal of Surgical Research·P V AnagnostopoulosG Suzuki
Aug 7, 2004·Journal of Vascular Surgery·Benjamin E HaithcockNervin H Fanous
May 12, 1998·Journal of Vascular Surgery·R P CambriaJ P Gertler
Aug 15, 2003·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·C-M Wahlgren, J Swedenborg
Jan 22, 2002·Journal of Vascular Surgery·Petros V AnagnostopoulosGeorge Suzuki
Apr 27, 2005·Transfusion Medicine Reviews·Claudio S Cinà, Catherine M Clase
Aug 9, 2005·Journal of Cardiothoracic and Vascular Anesthesia·Linda Shore-LessersonDavid L Reich
Jul 30, 2004·Anesthesia and Analgesia·Vance G NielsenDale A Parks
Oct 17, 2008·Journal of Cardiothoracic and Vascular Anesthesia·Claudia CrimiRichard P Cambria
Jan 1, 2016·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Ali KordzadehYiannis P Panayiotopoulos
Aug 9, 2002·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Nicholas J MorrisseyLarry H Hollier
Jul 10, 2019·Anaesthesia·F Monaco, P Nardelli
Jul 13, 2019·Vascular Specialist International·Eugenio Martelli, Jae Sung Cho
Apr 6, 2004·Critical Care Medicine·Siamak Barkhordarian, Alan Dardik
Mar 12, 2016·International Anesthesiology Clinics·James M Anton, Kaitlin J Herald
May 19, 1998·Progress in Cardiovascular Diseases·D J Wirthlin, R P Cambria

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