Coagulation disorders and bleeding in liver disease: future directions.

Clinics in Liver Disease
Stephen H Caldwell, A J Sanyal

Abstract

Much has changed since the characterization of the wide spectrum of abnormalities in the coagulation system in patients who have acute and chronic liver disease. With inherent limitations of conventional laboratory measures of coagulation in liver disease, it is now incumbent on us to explore how best to apply (or withhold) specific agents in specific situations. This will clearly require well focused translational research to understand and bring into sharp focus the various problems present, from dysfibrinogen to endogenous heparinoids, to uremia, to hyperfibrinolysis and even to unrecognized hypercoagulable conditions. The challenge lies ahead.

References

Jan 1, 1986·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A L BoksH H Van Vliet
Jul 27, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Laurent BellestAnnie Robert
Feb 29, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Armando Tripodi
May 17, 2008·Liver International : Official Journal of the International Association for the Study of the Liver·Ton LismanRobert J Porte

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Citations

Nov 26, 2013·Critical Care Nursing Clinics of North America·Carole L Mackavey, Robert Hanks
Mar 15, 2015·American Journal of Surgery·Mackenzie R CookUNKNOWN Northwest Trauma Research Collaboration
Jan 21, 2010·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Aida A Korish
May 18, 2019·Korean journal of anesthesiology·Klaus GörlingerTae-Yop Kim
May 24, 2014·The Journal of Trauma and Acute Care Surgery·Nikolay BugaevReuven Rabinovici
Oct 26, 2018·World Journal of Gastroenterology : WJG·Irina GîrleanuCătălin Sfarti

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