PMID: 8948311Nov 1, 1996Paper

Coagulation factor V gene mutation increases the risk of venous thrombosis in behçet's disease

British Journal of Rheumatology
A GülT Ozçelik

Abstract

We investigated the prevalence of the coagulation factor V gene G1691A mutation in 64 patients with Behçet's disease (BD) and in 107 apparently healthy individuals. The mutation was present in the heterozygous state in 37.5% of the patients with a history of deep vein thrombosis (12/32) and in 9.4% of the patients without any thrombotic event (3/32). Eleven healthy individuals were also heterozygous for the mutation (10.3%). The prevalence of the mutation in BD patients with and without thrombosis was significantly different (P = 0.0079). We conclude that the factor V gene mutation may play a major role in the development of venous thrombosis in BD.

Citations

Oct 31, 2003·Rheumatology International·Aşkin AteşMurat Duman
Apr 2, 2004·Rheumatology International·Zeki YesilovaIsmail H Kocar
Sep 14, 2006·Rheumatology International·Seong Ryul KwonWon Park
Jul 8, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·F Nilüfer YalçindağNejat Akar
Mar 20, 2013·Best Practice & Research. Clinical Rheumatology·Angelo L Gaffo
Apr 18, 2002·Thrombosis Research·Sedat KirazMeral Calgüneri
Aug 8, 2002·Thrombosis Research·Yun Jong LeeYeong Wook Song
Apr 13, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·R M Bertina
Jun 1, 1999·Clinical Neurology and Neurosurgery·J van KrimpenE Gomez Garcia
May 20, 1999·Clinics in Dermatology·T SaylanM Melikoğlu
Apr 1, 1997·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·J L Saver
May 26, 1999·Clinical and Laboratory Haematology·A M Cumming, C R Shiach
May 3, 2000·European Journal of Immunogenetics : Official Journal of the British Society for Histocompatibility and Immunogenetics·D H VerityM R Stanford
May 16, 2000·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·D MilhaudJ M Blard
Oct 14, 2004·Annals of the Rheumatic Diseases·M LeibaM Ehrenfeld
Nov 16, 2001·Annals of the Rheumatic Diseases·M LeibaM Ehrenfeld
Aug 21, 2003·The British Journal of Ophthalmology·D H VerityM R Stanford
Oct 21, 2011·Pathology Research International·Tamer İrfan Kaya
Feb 23, 2007·Gynecologic and Obstetric Investigation·Samet KafkasAli Riza Odabaşi
May 15, 2003·Current Rheumatology Reports·Hasan Yazici
Aug 13, 2013·Case Reports in Rheumatology·Nurşen DüzgünAşkın Ateş
Jun 5, 2003·Acta Ophthalmologica Scandinavica·Figen BatioğluDerya Beyza Sayin
Feb 8, 2007·International Journal of Immunogenetics·R GunesacarZ Ozbalkan
Jan 15, 2015·European Journal of Human Genetics : EJHG·Burcu Bakir-GungorOsman Ugur Sezerman
May 3, 2015·The American Journal of Case Reports·Yılmaz BaşAyşegül Taylan Özkan
Apr 18, 2015·Thrombosis Journal·Giacomo EmmiDomenico Prisco
Apr 8, 2011·Thrombosis Research·Serhat BirengelFigen Batıoğlu
Mar 21, 2007·Joint, Bone, Spine : Revue Du Rhumatisme·Cengiz KorkmazMahmut Kebapçi
Sep 26, 2003·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·M Akif OztürkIbrahim C Haznedaroglu
Dec 10, 1999·Rheumatology·A GülT Ozçelik
Dec 29, 2011·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·M Cem ArHasan Yazici
Feb 23, 2005·Journal of Dental Research·L M Al-OtaibiT W J Poate
Jul 5, 2001·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·A I RussellD O Haskard
Aug 11, 2000·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·M MisgavA S Berliner

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.