Coal tar therapy in palmoplantar psoriasis: old wine in an old bottle?

International Journal of Dermatology
B KumarInderjeet Kaur

Abstract

Palmoplantar psoriasis (PPP) is a disabling condition which is usually resistant to most of the available therapeutic modalities. Coal tar is an accepted therapy for psoriasis which has not been well studied for PPP. Thirty patients with a plaque type of PPP were allocated into two groups: Group A (19 patients) were treated with 6% crude coal tar (CCT) ointment and Group B (11 patients) were treated with white petrolatum and salicylic acid. In both groups, ointment was applied and left on overnight. Wearing of gloves and socks during the night and application of emollients in the day was routinely advised. The lesions were assessed for erythema, scaling, and induration (ESI) every 2 weeks for a total of 8 weeks. Patients with greater than 50% improvement were considered to have good improvement. Side-effects, if any, were also monitored. In Group A, 76.5% of patients (13/17) showed good improvement, whereas only 45.5% of patients (5/11) in Group B showed the same magnitude of improvement (P < 0.05). No side-effects were reported by any patient in either of the groups. Crude coal tar is a safe, effective, and inexpensive modality for the treatment of PPP. We recommend coal tar under occlusion, along with the liberal use of emoll...Continue Reading

Citations

Mar 4, 2000·Clinics in Dermatology·L C Parish, J A Witkowski
Jan 1, 2008·Advances in Dermatology·Kelly M Cordoro
Sep 28, 2010·Dermatologic Therapy·Sagi LiorPavlotsky Felix
Dec 5, 2009·Journal of Cosmetic Dermatology·Amit BhatiaOm Prakash Katare
Mar 7, 2012·The Journal of Dermatological Treatment·Shiu-Chung AuAlice B Gottlieb
Jan 21, 2020·The Cochrane Database of Systematic Reviews·Grace ObeidLaurence Le Cleach
Jan 27, 2006·The Cochrane Database of Systematic Reviews·A M MarslandC E M Griffiths
Sep 14, 2007·The Journal of Dermatological Treatment·Amit BhatiaOm Prakash Katare

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