PMID: 6968906Jul 1, 1980Paper

Coated pits act as molecular filters

Proceedings of the National Academy of Sciences of the United States of America
M S BretscherB M Pearse

Abstract

Two proteins--theta and H63 antigens--are found to be excluded from coated pits on fibroblast plasma membranes. Coated pits thus act as molecular filters, pinching off, into the cell, lipid vesicles containing a limited number of specific receptors but excluding other plasma membrane proteins. This constitutes part of a lipid flow cycle that was proposed earlier to explain the capping of crosslinked surface antigens.

References

Jul 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·R G AndersonM S Brown
Jun 21, 1979·Nature·J L GoldsteinM S Brown
Dec 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·R MontesanoL Orci
Oct 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·P GordenL Orci
Sep 1, 1979·The Journal of Cell Biology·P L Stern, M S Bretscher
Apr 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·B M Pearse
Apr 1, 1976·The Journal of Cell Biology·W W FrankeT W Keenan
Mar 4, 1976·Nature·M S Bretscher
Jul 1, 1973·The Journal of Cell Biology·R Rodewald
Nov 1, 1967·The Journal of Cell Biology·D S Friend, M G Farquhar
Feb 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J E Rothman, R E Fine
Jan 1, 1962·Cold Spring Harbor Symposia on Quantitative Biology·P I MARCUS
Feb 1, 1964·The Journal of Cell Biology·T F ROTH, K R PORTER

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Citations

Jun 1, 1987·Cell and Tissue Research·S BursztajnS A Berman
Jul 1, 1990·The Journal of Membrane Biology·M P LisantiA R Saltiel
Jul 11, 1984·Biochimica Et Biophysica Acta·R J PeaseT J Peters
Mar 1, 1983·Developmental Biology·D F Woods, C A Poodry
Aug 13, 1984·Life Sciences·P L GutierrezR Pottathil
Jan 1, 1990·Toxicon : Official Journal of the International Society on Toxinology·M RojasF Zambrano
Sep 1, 1990·Brain Research. Brain Research Reviews·R K Calverley, D G Jones
Oct 1, 1988·Immunology Letters·P J Robinson, S C Spencer
Dec 6, 1989·Biochimica Et Biophysica Acta·M G Low
Jul 23, 2011·Nature Reviews. Molecular Cell Biology·Harvey T McMahon, Emmanuel Boucrot
Jan 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·B M Pearse
Dec 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·R M Smith, L Jarett
Mar 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·A ColombattiJ T August
Sep 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·M C Willingham, I Pastan
Jan 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·M S Bretscher
Jul 1, 1986·The Journal of Cell Biology·N L KedershaL H Rome
Feb 1, 1988·The Journal of Cell Biology·M S Bretscher, M S Bretcher
Jun 1, 1989·The Journal of Cell Biology·A P Turkewitz, S C Harrison
May 1, 1990·The Journal of Cell Biology·P LemanskyA M Tartakoff
Oct 1, 1990·The Journal of Cell Biology·A Le BivicE Rodriguez-Boulan
Dec 1, 1992·The Journal of Cell Biology·M J SchellA L Hubbard
Jun 1, 1994·The Journal of Cell Biology·S L ShyngD A Harris
Dec 1, 1981·The Journal of Cell Biology·R A Crowther, B M Pearse
Jan 1, 1983·The Journal of Cell Biology·P F PilchR E Fine
Apr 1, 1984·The Journal of Cell Biology·D KerjaschkiM G Farquhar

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