PMID: 7017287Mar 1, 1981Paper

Coca and cocaine as medicines: an historical review

Journal of Ethnopharmacology
L Grinspoon, J B Bakalar

Abstract

Coca has been used in folk medicine in South America for thousands of years both as a general stimulant and for more specific medical purposes. It remains one of the most commonly used medicines in some areas of Bolivia and Peru. The medical use of coca and cocaine in the industrial world has a more dramatic and varied history. Coca extract and cocaine were introduced as pancreas for a wide variety of complaints in the late 19th century. Cocaine was the first effective local anesthetic; prescription drugs, patent medicine, and soda drinks containing it were also popular. When its dangers became apparent and substitutes became available, its medical use went into decline, especially when, in the 1930s, amphetamine began to replace it for some purposes. Today its only generally accepted medical use is as a topical anesthetic in certain kinds of minor surgery and other clinical procedures. There are, however, some recent and so far uncertain signs of reviving interest in cocaine and even coca itself for other medical purposes, in research as well as in diagnosis and treatment.

References

Jul 17, 1976·Canadian Medical Association Journal·R MelzackB M Mount
Nov 19, 1977·British Medical Journal·R Twycross
Jun 18, 1974·Psychopharmacologia·R M PostF K Goodwin

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Citations

Sep 18, 2003·The Journal of Legal Medicine·Sana Loue
Oct 29, 2015·Wilderness & Environmental Medicine·Amy Sue Biondich, Jeremy D Joslin
Jan 1, 1985·Survey of Ophthalmology·A J AltmanG A Fournier
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Dec 5, 2019·Tropical Diseases, Travel Medicine and Vaccines·Irmgard Bauer
Feb 19, 2016·Journal of Separation Science·Rodrigo Alves Soares CruzGilda Guimarães Leitão
Mar 12, 2021·Cardiovascular Research·Fabian Philipp KreutzerThomas Thum
Apr 29, 2021·Chemical Society Reviews·Cooper S JamiesonJohn M Billingsley

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