PMID: 11930524Apr 5, 2002Paper

Cocaine: effects of in utero exposure on the fetus and neonate

The Journal of Perinatal & Neonatal Nursing
D F Askin, B Diehl-Jones

Abstract

In North America, an increasing number of babies are prenatally exposed to cocaine, yet the implications of cocaine use during pregnancy are not fully understood. The effects of cocaine are exerted primarily by its influence on aminergic receptors in the central and peripheral nervous systems. Developmental, physiological, and behavioral problems in infants and children are likely outcomes of maternal cocaine abuse, but these findings are confounded by concomitant use of other drugs such as marijuana and cocaine and by factors such as time, dosage, and route of cocaine intake. Different screening options exist for cocaine and its metabolites, including sampling of neonatal urine, hair and meconium need to be considered, as do the sensitivity and the ethical implications of such testing. Clinical management of cocaine-exposed infants requires attention to several issues, including: central nervous system irritation, cardiac anomalies, apnea, and feeding difficulties, as well as infant safety and follow-up postdischarge. Early detection and intervention remain the primary objectives of caring for cocaine-exposed infants.

References

May 1, 1992·Pediatric Pathology·J KleinG Koren
May 1, 1992·American Journal of Public Health·J G FeldmanM Salwen
Jun 1, 1992·American Journal of Obstetrics and Gynecology·F F BroekhuizenC Van Mullem
Sep 18, 1991·JAMA : the Journal of the American Medical Association·C S PhibbsR M Schwartz
Jul 1, 1991·Teratology·R P KapurT H Shepard
Feb 1, 1991·American Journal of Diseases of Children·S J KharaschJ Sargent
Feb 1, 1991·Current Problems in Cardiology·J M Isner, S K Chokshi
Apr 1, 1991·Journal of Pediatric Surgery·C CzyrkoA J Ross
Jan 1, 1990·American Journal of Public Health·D B Petitti, C Coleman
Dec 15, 1989·JAMA : the Journal of the American Medical Association·K GrahamM Greenwald
Aug 1, 1988·The Journal of Pediatrics·T M DoberczakS R Kandall
Apr 1, 1987·Pediatric Clinics of North America·R G MacKenzieA J Haftel
Sep 1, 1987·American Journal of Obstetrics and Gynecology·S N MacGregorJ P Minogue
Oct 1, 1987·The Journal of Pediatrics·A S Oro, S D Dixon
Feb 20, 1987·JAMA : the Journal of the American Medical Association·J R WoodsK E Clark
Mar 1, 1986·The Journal of Pediatrics·I J ChasnoffC M Stack
Sep 12, 1985·The New England Journal of Medicine·I J ChasnoffK A Burns
Sep 1, 1985·Clinical Pharmacology and Therapeutics·M J ChowM W Fischman
Nov 1, 1993·The International Journal of the Addictions·M Behnke, F D Eyler
Oct 1, 1993·Journal of Pediatric Psychology·M BlackP Nair
Oct 1, 1994·Drug and Alcohol Dependence·D R Neuspiel
May 1, 1995·Journal of Analytical Toxicology·D E LewisA Koller
Jun 1, 1995·Pediatric Emergency Care·N M RosenbergR E Kauffman
Apr 1, 1995·Journal of Developmental and Behavioral Pediatrics : JDBP·F R SalleeG Sethuraman
Jan 5, 1995·Forensic Science International : Synergy·G Koren
Mar 1, 1995·American Journal of Obstetrics and Gynecology·H WehbehH L Minkoff
Nov 1, 1994·Archives of Pediatrics & Adolescent Medicine·J J FrassicaS E Lipshultz
Oct 1, 1994·The Journal of Pediatrics·H AkinbiV K Bhutani
Sep 1, 1994·Clinical Pediatrics·M L AngelilliR J Sokol
Mar 1, 1994·Pediatrics in Review·J Wootton, S I Miller
Sep 1, 1994·Archives of Pediatrics & Adolescent Medicine·L SingerR Kliegman
Jan 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·G A Richardson, N L Day
May 1, 1994·The Journal of Pediatrics·R M KliegmanT Yamashita
Jul 1, 1993·Southern Medical Journal·J E EllisC A Patterson-Barnett
Feb 1, 1993·American Journal of Public Health·D A BatemanM C Heagarty
Feb 1, 1993·American Journal of Obstetrics and Gynecology·P SamuelsK R McCrae
Mar 1, 1993·Clinical Pharmacology and Therapeutics·S SchenkerT S King
Mar 1, 1993·Pediatric Neurology·C A ChiribogaW A Hauser
Oct 1, 1996·The Journal of Pediatrics·S W JacobsonL M Chiodo

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Citations

Dec 23, 2003·European Journal of Obstetrics, Gynecology, and Reproductive Biology·O Fajemirokun-Odudeyi, S W Lindow
Mar 21, 2002·Paediatric Anaesthesia·Cynthia A VoelkerRoger M Hinson
Mar 3, 2010·Ultrastructural Pathology·Jacques Gilloteaux, Nelson N Ekwedike
Oct 20, 2009·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·C LejeuneP Gressens
Apr 6, 2004·The Nursing Clinics of North America·Andrea Kovalesky
Aug 9, 2001·Prenatal Diagnosis
Jan 1, 2013·International Journal of High Risk Behaviors & Addiction·Iraj SahramianElham Sharafi

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