PMID: 2496428Jan 1, 1989Paper

Cocaine-induced cocaine craving

Psychopharmacology
J H JaffeM A Sherer

Abstract

In nine experienced users of cocaine, we examined the urge to use cocaine or other drugs following a 40 mg dose of intravenous (IV) cocaine with and without oral pretreatment with 2.5 mg bromocriptine. The urge to use cocaine was assessed with a questionnaire constructed to assess both "wanting" and "craving" for cocaine or other drugs. Fifteen minutes after the administration of cocaine (but not after placebo), subjects' ratings for both drug "wanting" and drug "craving" were significantly increased. Our results provide a laboratory demonstration of cocaine-induced increases in the urge to use drugs in humans. The findings, stressing the role of internal stimuli associated with drug administration, suggest the possibility of distinguishing among related, but perhaps distinct, components of the fluctuating levels of motivation to reuse drugs.

References

Jan 1, 1977·Journal of Neuroscience Research·D Taylor, B T Ho
Jan 1, 1979·Behaviour Research and Therapy·T B Baker, D S Cannon
Nov 1, 1975·Pharmacology, Biochemistry, and Behavior·G J Gerber, R Stretch
Mar 11, 1977·Science·C P O'BrienB Wells
Feb 1, 1989·Psychiatry Research·M A ShererJ H Jaffe
May 18, 1985·Lancet·C A Dackis, M S Gold
Dec 6, 1986·Lancet·K KumorJ Jaffe
Jan 1, 1985·Neuroscience and Biobehavioral Reviews·C A Dackis, M S Gold
Jan 1, 1986·Journal of Substance Abuse Treatment·W E McAuliffe, J M Ch'ien
Dec 1, 1988·Biological Psychiatry·M A Sherer
Jan 1, 1986·Journal of Substance Abuse Treatment·A R ChildressC P O'Brien
Mar 1, 1987·Archives of General Psychiatry·C A DackisD R Sweeney
Jan 1, 1985·International Journal of Psychiatry in Medicine·C A DackisD R Sweeney
Jan 1, 1985·Journal of Substance Abuse Treatment·C A Dackis, M S Gold
Feb 1, 1986·Archives of General Psychiatry·F H Gawin, H D Kleber
Apr 1, 1974·Archives of General Psychiatry·A M LudwigL H Stark
Jan 1, 1973·The International Journal of the Addictions·J D Teasdale
Feb 1, 1982·Atherosclerosis·M Indira, P A Kurup
Jan 1, 1983·Psychopharmacology·H de Wit, J Stewart
Jan 1, 1981·Psychopharmacology·H de Wit, J Stewart
Feb 1, 1982·Archives of General Psychiatry·B J RounsavilleC Wilber
Dec 1, 1982·Pharmacology, Biochemistry, and Behavior·R de la Garza, C E Johanson
May 1, 1980·The International Journal of the Addictions·S I Sideroff, M E Jarvik

❮ Previous
Next ❯

Citations

Jan 1, 1993·Psychopharmacology·A MarkouG F Koob
Jul 1, 1995·Psychopharmacology·A SmithD C Roberts
Apr 1, 1996·Psychopharmacology·A EttenbergT D Geist
Jan 1, 1990·Psychopharmacology·M E CarrollD A Sadoff
Sep 1, 1996·Psychopharmacology·C ChiamuleraM Tessari
Jun 15, 2007·Psychopharmacology·Ayelet CooperAbraham Zangen
May 17, 2008·Psychopharmacology·Leigh C P BotlyPaul J Fletcher
Feb 18, 2009·Psychopharmacology·Porche' Kirkland Henry, Leonard L Howell
Sep 26, 2009·Psychopharmacology·Matthew W FeltensteinRonald E See
Nov 20, 2009·Psychopharmacology·Leonard L HowellKimberly P Lindsey
Jul 1, 1992·Biological Psychiatry·G KnoblichR King
Jan 1, 1993·Life Sciences·K D Nantwi, E P Schoener
Aug 1, 1989·Pharmacology, Biochemistry, and Behavior·K KumorJ Jaffe
Dec 1, 1994·Pharmacology, Biochemistry, and Behavior·C M Knapp, C Kornetsky
Jan 1, 1994·Neuroscience and Biobehavioral Reviews·J M Witkin
Sep 1, 1993·Brain Research. Brain Research Reviews·T E Robinson, K C Berridge
May 1, 1992·Trends in Pharmacological Sciences·W L Woolverton, K M Johnson
Sep 1, 1995·Addictive Behaviors·A DroungasC P O'Brien
Mar 1, 1995·Drug and Alcohol Dependence·R W FoltinF R Levin
May 12, 2004·Behavioural Brain Research·Judith R HombergTaco J de Vries
Jun 12, 2013·Neuropharmacology·Terry E RobinsonBenjamin T Saunders
Jul 26, 2002·Brain Research·Andrew B NormanVladimir L Tsibulsky
Apr 9, 2002·European Journal of Pharmacology·Roman StefanskiSteven R Goldberg

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.