PMID: 9523545Apr 2, 1998Paper

Cocaine-induced peripheral vascular occlusive disease--a case report

Angiology
A GutierrezW C Krupski

Abstract

Two patients with cocaine-induced peripheral vascular occlusive disease are presented. A 37-year-old man was admitted to the hospital for evaluation of severe pain and numbness of his feet. He had used cocaine prior to admission. Arteriography showed bilateral occlusions of superficial femoral, popliteal, and trifucation arteries. Despite repeated infusions of urokinase, he developed progressive bilateral gangrene of both legs necessitating bilateral below-knee amputations. The second patient developed similar symptoms after smoking cocaine. Arteriography showed vasospasm bilaterally from the iliac arteries distally. I.v. nitroglycerin infusion caused resolution of the vasospasm and ischemic symptoms.

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Citations

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Dec 18, 2008·Actas dermo-sifiliográficas·E RocheV Alegre de Miquel
Oct 25, 2006·Annals of Emergency Medicine·Saurabh S Dhawan, Benjamin W E Wang
Nov 7, 1999·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·H J SchneiderK G Burnand
Feb 27, 2016·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·John R RichardsRichard A Lange
Feb 6, 2009·The Annals of Pharmacotherapy·Szu-Chia ChenJer-Ming Chang
Mar 16, 2007·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Antonino MazzoneRoberta Pacifici
Dec 18, 2019·International Journal of Environmental Research and Public Health·Patricia P WadowskiRenate Koppensteiner

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