Cocaine-induced renal disease

Expert Opinion on Drug Safety
Michael D Gitman, Pravin C Singhal

Abstract

Cocaine has anaesthetic, vasoconstrictive and CNS stimulatory effects. Presently, it is used clinically as a local anaesthetic and abused as a recreational drug. It has been implicated in both acute and chronic renal failure and has been reported to affect every aspect of the nephron. This article will review the spectrum of cocaine-induced kidney disease and attempt to give insight into the pathophysiological mechanisms involved.

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Citations

Aug 2, 2013·The Journal of Infectious Diseases·Gregory M LucasUNKNOWN NA-ACCORD of the IeDEA
Feb 7, 2016·Clinical and Experimental Pharmacology & Physiology·Huynh Nhu MaiHyoung-Chun Kim
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Jun 11, 2020·Journal of Investigative Medicine High Impact Case Reports·Faisal InayatRaquel M Rosen
Jan 30, 2021·Radiology Case Reports·Hannah LambergJohn D Millet

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