Cochlear spike synchronization and neuron coincidence detection model

Chaos
Rolf Bader

Abstract

Coincidence detection of a spike pattern fed from the cochlea into a single neuron is investigated using a physical Finite-Difference model of the cochlea and a physiologically motivated neuron model. Previous studies have shown experimental evidence of increased spike synchronization in the nucleus cochlearis and the trapezoid body [Joris et al., J. Neurophysiol. 71(3), 1022-1036 and 1037-1051 (1994)] and models show tone partial phase synchronization at the transition from mechanical waves on the basilar membrane into spike patterns [Ch. F. Babbs, J. Biophys. 2011, 435135]. Still the traveling speed of waves on the basilar membrane cause a frequency-dependent time delay of simultaneously incoming sound wavefronts up to 10 ms. The present model shows nearly perfect synchronization of multiple spike inputs as neuron outputs with interspike intervals (ISI) at the periodicity of the incoming sound for frequencies from about 30 to 300 Hz for two different amounts of afferent nerve fiber neuron inputs. Coincidence detection serves here as a fusion of multiple inputs into one single event enhancing pitch periodicity detection for low frequencies, impulse detection, or increased sound or speech intelligibility due to dereverberation.

References

Feb 1, 1978·The Journal of the Acoustical Society of America·J L GoldsteinM Furst
Jan 1, 1977·The Journal of the Acoustical Society of America·J B Allen
May 1, 1981·The Journal of the Acoustical Society of America·S T Neely
Jun 1, 1996·The Journal of the Acoustical Society of America·T DauA Kohlrausch
Jun 1, 1996·The Journal of the Acoustical Society of America·T DauA Kohlrausch
Jun 6, 1998·Proceedings of the National Academy of Sciences of the United States of America·H MarkramM Tsodyks
Mar 16, 2002·Nature Neuroscience·Michael S Lewicki
May 15, 2004·Cerebral Cortex·Eugene M IzhikevichGerald M Edelman
Oct 9, 2007·Journal of Cognitive Neuroscience·Anne CaclinMarie-Hélène Giard
Sep 23, 2010·Biophysical Journal·Sripriya RamamoorthyAlfred L Nuttall
Mar 2, 2012·Neural Networks : the Official Journal of the International Neural Network Society·Cornelius GlackinJohn Wade
Feb 13, 2016·Physical Review. E·Sarah A M LoosAnna Zakharova

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