Cochrane review on the role of surgery in cervical spondylotic radiculomyelopathy

Spine
Ioannis P FouyasPeter Ag Sandercock

Abstract

This study involved a search of MEDLINE (1966 to 2000), EMBASE (1980 to 2000), and the Cochrane Controlled Trials Register. The authors of the identified randomized controlled trials were contacted to detect any additional published or unpublished data. The trials selected for this study included all the truly unconfounded or quasi-randomized controlled investigations allocating patients with cervical radiculopathy or myelopathy to 1) "best medical management" or "decompressive surgery (with or without some form of fusion) plus best medical management," or 2) "early decompressive surgery" or "delayed decompressive surgery." Two reviewers independently selected trials for inclusion, assessed trial quality, and extracted the data. To determine whether surgical treatment of cervical radiculopathy or myelopathy is associated with improved outcome, as compared with conservative management, and whether the timing of surgery (immediate or delayed because of persistence or progression of relevant symptoms and signs) has an impact on outcome. Cervical spondylosis causes pain and disability by compressing the spinal cord or roots. Surgery to relieve the compression may reduce the pain and disability. However, it is associated with a smal...Continue Reading

References

Mar 1, 1976·Journal of Neurosurgery·A N Martins
Sep 1, 1991·Journal of Spinal Disorders·E C BenzelT Hadden
Nov 1, 1991·Neurosurgery·D P van Berge HenegouwenC vd Werken
Feb 1, 1990·Neurosurgery·T F MehalicB I Applebaum
Jan 1, 1989·Acta neurochirurgica·H Bertalanffy, H R Eggert
Jan 1, 1984·Journal of Neurology, Neurosurgery, and Psychiatry·M P Barnes, M Saunders
May 1, 1995·Journal of Neurosurgery·M J EbersoldL M Quast
Dec 1, 1996·Annals of the Rheumatic Diseases·A T CaseyH A Crockard
Feb 1, 1997·British Journal of Neurosurgery·R F Hafez, H A Crockard
Jan 1, 1997·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·L C PerssonC A Carlsson
Jan 1, 1954·Brain : a Journal of Neurology·C PALLISJ D SPILLANE
Sep 1, 1956·Brain : a Journal of Neurology·E CLARKE, P K ROBINSON
Nov 1, 1958·Journal of Neurosurgery·R B CLOWARD
Dec 28, 1963·British Medical Journal·F LEES, J W TURNER
May 22, 1965·Lancet·D H IRVINEB N KLUKVIN

❮ Previous
Next ❯

Citations

Oct 13, 2006·European Radiology·Fouad FayadMichel Revel
Nov 18, 2005·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·C RöderM Aebi
Dec 5, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Anneli Peolsson
Jul 4, 2012·HSS Journal : the Musculoskeletal Journal of Hospital for Special Surgery·Darren R LeblPatrick F O'Leary
Oct 2, 2012·HSS Journal : the Musculoskeletal Journal of Hospital for Special Surgery·John M CaridiAlexander P Hughes
Jul 29, 2005·The New England Journal of Medicine·Simon Carette, Michael G Fehlings
Feb 13, 2004·The New England Journal of Medicine·Richard A DeyoSohail K Mirza
Jul 4, 2009·Regional Anesthesia and Pain Medicine·Samer N NarouzeNagy Mekhail
Feb 7, 2008·Spine·Eugene J CarrageeUNKNOWN Bone and Joint Decade 2000-2010 Task Force on Neck Pain and Its Associated Disorders
Feb 7, 2008·Spine·Eric L HurwitzUNKNOWN Bone and Joint Decade 2000-2010 Task Force on Neck Pain and Its Associated Disorders
May 7, 2010·The Neurologist·Jennifer A Tracy, J D Bartleson
Mar 10, 2007·BMJ : British Medical Journal·Allan I Binder
Aug 18, 2005·Hand Surgery : an International Journal Devoted to Hand and Upper Limb Surgery and Related Research : Journal of the Asia-Pacific Federation of Societies for Surgery of the Hand·C S ChowP C Ho
Jun 25, 2004·Neurosurgery·George VranosJohn P A Ioannidis
Oct 17, 2008·Journal of the American Veterinary Medical Association·Ronaldo C da CostaGabrielle Monteith
Oct 11, 2011·Journal of Neurosurgery. Spine·Masatoshi SumiKoki Uno
Jun 14, 2005·Journal of Neurosurgery. Spine·Joseph T KingMark S Roberts
Oct 21, 2005·Journal of Neurosurgery. Spine·Paul R Cooper
Jan 1, 2012·Surgical Neurology International·Alvaro CamperoPablo Ajler
Apr 16, 2014·BMC Musculoskeletal Disorders·Sarita van GeestCarmen Vleggeert-Lankamp
Feb 8, 2014·BMC Musculoskeletal Disorders·Anneli PeolssonHåkan Löfgren
Oct 30, 2012·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Marienke van MiddelkoopArianne P Verhagen
Mar 14, 2007·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Michael Benatar
Apr 25, 2014·The Medical Clinics of North America·Ginger Evans
May 7, 2015·Journal of the Chinese Medical Association : JCMA·Kuang-Ting YehWen-Tien Wu
Apr 20, 2010·The Orthopedic Clinics of North America·Eric Klineberg
Nov 14, 2006·The Spine Journal : Official Journal of the North American Spine Society·Paul G Matz
Oct 16, 2015·Regional Anesthesia and Pain Medicine·Shrif J CostandiNagy A Mekhail
Nov 2, 2012·Pain Practice : the Official Journal of World Institute of Pain·Mehul J DesaiAjay Dharmappa
Apr 22, 2014·Journal of Manipulative and Physiological Therapeutics·Anneli PeolssonGunnel Peterson
Sep 10, 2015·JAAPA : Official Journal of the American Academy of Physician Assistants·Elizabeth SaterenZollerManish Sharma
Mar 4, 2015·The Spine Journal : Official Journal of the North American Spine Society·Martin SkeppholmClaes Olerud
Feb 25, 2014·The Spine Journal : Official Journal of the North American Spine Society·Benjamin M EllingsonLangston T Holly

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.