Cocrystals of 2,6-dichloroaniline and 2,6-dichlorophenol plus three new pseudopolymorphs of their coformers

Acta Crystallographica. Section C, Structural Chemistry
Valeska Gerhardt, Michael Bolte

Abstract

The structures of cocrystals of 2,6-dichlorophenol with 2,4-diamino-6-methyl-1,3,5-triazine, C6H4Cl2O·C4H7N5, (III), and 2,6-dichloroaniline with 2,6-diaminopyrimidin-4(3H)-one and N,N-dimethylacetamide, C6H5Cl2N·C4H6N4O·C4H9NO, (V), plus three new pseudopolymorphs of their coformers, namely 2,4-diamino-6-methyl-1,3,5-triazine-N,N-dimethylacetamide (1/1), C4H7N5·C4H9NO, (I), 2,4-diamino-6-methyl-1,3,5-triazine-N-methylpyrrolidin-2-one (1/1), C4H7N5·C5H9NO, (II), and 6-aminoisocytosine-N-methylpyrrolidin-2-one (1/1), C4H6N4O·C5H9NO, (IV), are reported. Both 2,6-dichlorophenol and 2,6-dichloroaniline are capable of forming definite synthon motifs, which usually lead to either two- or three-dimensional crystal-packing arrangements. Thus, the two isomorphous pseudopolymorphs of 2,4-diamino-6-methyl-1,3,5-triazine, i.e. (I) and (II), form a three-dimensional network, while the N-methylpyrrolidin-2-one solvate of 6-aminoisocytosine, i.e. (IV), displays two-dimensional layers. On the basis of these results, attempts to cocrystallize 2,6-dichlorophenol with 2,4-diamino-6-methyl-1,3,5-triazine, (III), and 2,6-dichloroaniline with 6-aminoisocytosine, (V), yielded two-dimensional networks, whereby in cocrystal (III) the overall structure ...Continue Reading

References

Aug 26, 1998·Nature·L M McMurryS B Levy
Jun 22, 2001·Acta Crystallographica. Section D, Biological Crystallography·P J Loll
Nov 14, 2001·Acta Crystallographica. Section C, Crystal Structure Communications·J Eriksson, L Eriksson
Jan 26, 2006·Acta Crystallographica. Section B, Structural Science·Doyle Britton
Dec 25, 2007·Acta Crystallographica. Section A, Foundations of Crystallography·George M Sheldrick
Dec 25, 2009·Journal of Fluorescence·Hong-Mei ZhangYan-Qing Wang
Mar 9, 2010·Journal of Hazardous Materials·Ying WangXiaochun Chen
Feb 1, 1995·Toxicology in Vitro : an International Journal Published in Association with BIBRA·M A ValentovicG O Rankin
May 5, 2011·Acta Crystallographica. Section C, Crystal Structure Communications·Valeska GerhardtMichael Bolte
Jan 1, 2010·Acta Crystallographica. Section E, Structure Reports Online·Xiu-Ying QinJia-Xun Lin
Jul 15, 2011·Acta Crystallographica. Section E, Structure Reports Online·Wan-Qiang Wang
Aug 13, 2011·Acta Crystallographica. Section E, Structure Reports Online·Peng LiuHai-Bo Wang
Mar 12, 2013·Acta Crystallographica. Section E, Structure Reports Online·Gertruida J S VenterAndreas Roodt
Jan 3, 2014·Angewandte Chemie·Colin R Groom, Frank H Allen
Dec 3, 2014·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Mirosław SzafranZofia Dega-Szafran
Apr 2, 2015·Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials·Valeska Gerhardt, Ernst Egert

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Acta Crystallographica. Section C, Structural Chemistry
Wilhelm Maximilian Hützler, Ernst Egert
Acta Crystallographica. Section B, Structural Science
Maya TutughamiarsoErnst Egert
© 2021 Meta ULC. All rights reserved