PMID: 6966679Apr 1, 1980Paper

Coded-aperture imaging of the heart

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
W L RogersJ W Keyes

Abstract

Coded-aperture imaging of the heart combines the advantages of tomography with good sensitivity, high resolution, and accurate size scaling. Since the images are multiplexed, the method may be adapted to small, portable cameras for bed-side use without sacrificing image resolution. A new coded aperture designed especially for cardiac imaging has been constructed and tested. This aperture incorporates significant improvements over previous designs. Longitudinal tomograms are calculated at 1-cm intervals using a modified ART algorithm. Experimental lateral resulution at 140 keV with a portable scintillation camera is 3.8 mm FWHM at 4 cm, and 7.8 mm FWHM at 12 cm. Dpth resolution determined from a sloping line source is 1.1 cm FWHM at 4 cm, and 2.9 cm at 12 cm. The calculated point-source sensitivities in air at 4 cm and 12 cm, respectively, are 20 and 8 cps/microCi. Images of good diagnostic quality have been obtained in phantoms and in a dog model of acute myocardial infarction, using thallium-201, technetium-99m pyrophosphate, and gated ventricular blood-pool imaging with Tc-labeled red blood cells. Preliminary studies in humans confirm the good results in animals.

Citations

May 14, 2011·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Hirofumi FujiiJohn V Frangioni
Dec 1, 1983·International Journal of Radiation Oncology, Biology, Physics·W R Hendee
Feb 5, 2010·JACC. Cardiovascular Imaging·David M Raffel, Donald M Wieland
Jan 1, 1986·IEEE Transactions on Medical Imaging·J W Van GiessenH J Dane
Aug 4, 2009·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·J MejiaM V Simões

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