PMID: 9541855May 23, 1998Paper

Codeine testing in sweat and saliva with the Drugwipe

International Journal of Legal Medicine
Pascal KintzB Ludes

Abstract

With the growing interest in drug testing within different sectors of society, there has become a need for drug assays that can be performed immediately at the site of specimen collection. Recently, Securetec (Ottobrunn, Germany) has introduced the Drugwipe, a non instrument-based, on-site immunodiagnostic assay for the detection of drugs on surfaces. Different tests are available for opiates, cocaine and cannabis. To document the applications of the Drugwipe "opiate" on human biological fluids, 60 mg codeine phosphate were orally administered to 6 subjects. First, sweat testing with the Drugwipe was studied. The wiping section of the kit was used to swab the forehead of the subjects for 10 s, at 1, 4, 9 and 24 h after codeine administration. At the same time, for each period, a sweat patch (Pharmchek, USA) was applied to the outer portion of the upper arm. Codeine was then quantified in the patch by GC/MS and the measured concentrations used as reference. In all subjects except one the Drugwipe tested positive for opiates, however with few false negative results. In the second part of the study, results of the Drugwipe were compared with those obtained by GC/MS for saliva. The tongue of the subjects was carefully wiped over a ...Continue Reading

Citations

Jul 24, 2010·International Journal of Legal Medicine·Anna PehrssonPirjo Lillsunde
Mar 21, 2006·Rapid Communications in Mass Spectrometry : RCM·Pamela CámporaPurificación Fernández
Jul 13, 2006·Forensic Science International : Synergy·Thomas KellerFabio Monticelli
Aug 10, 2000·Baillière's Best Practice & Research. Clinical Endocrinology & Metabolism·L Rivier
Nov 29, 2007·Therapeutic Drug Monitoring·Jaime LozanoSimona Pichini
Mar 3, 2007·Annals of the New York Academy of Sciences·Edward J Cone, Marilyn A Huestis
Jun 3, 2006·Clinical Chemistry·Eugene W SchwilkeMarilyn A Huestis
Nov 26, 1999·Journal of Chromatography. B, Biomedical Sciences and Applications·M A HuestisR E Joseph

❮ Previous
Next ❯

Related Concepts

Related Feeds

Addiction

This feed focuses mechanisms underlying addiction and addictive behaviour including heroin and opium dependence, alcohol intoxication, gambling, and tobacco addiction.