DOI: 10.1101/507061Dec 27, 2018Paper

Coding advantage of grid cell orientation under noisy conditions

BioRxiv : the Preprint Server for Biology
Dong ChenWen-Xu Wang

Abstract

Grid cells constitute a crucial component of the “GPS” in the mammalian brain. Recent experiments revealed that grid cell activity is anchored to environmental boundaries. More specifically, these results revealed a slight yet consistent offset of 8 degrees relative to boundaries of a square environment. The causes and possible functional roles of this orientation are still unclear. Here we propose that this phenomenon maximizes the spatial information conveyed by grid cells. Computer simulations of the grid cell network reveal that the universal grid orientation at 8 degrees optimizes spatial coding specifically in the presence of noise. Our model also predicts the minimum number of grid cells in each module. In addition, analytical results and a dynamical reinforcement learning model reveal the mechanism underlying the noise-induced orientation preference at 8 degrees. Together, these results suggest that the experimentally observed common orientation of grid cells serves to maximize spatial information in the presence of noise.

Related Concepts

Brain
Environment
Psychological Orientation
Spatial Distribution
Modulated
Simulation
Research Study
Cell Activation
Orientation (spatial)
Grid Cells

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