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Coding coenzyme handles: a hypothesis for the origin of the genetic code

Proceedings of the National Academy of Sciences of the United States of America

Nov 1, 1993

Eörs Szathmáry

PMID: 8234335

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Abstract

The coding coenzyme handle hypothesis suggests that useful coding preceded translation. Early adapters, the ancestors of present-day anticodons, were charged with amino acids acting as coenzymes of ribozymes in a metabolically complex RNA world. The ancestral aminoacyl-adapter synthetas...read more

Mentioned in this Paper

Amino Acyl-tRNA Synthetases
Catalytic RNA
Coenzymes
Transfer RNA
Introns
Genetic Code
Biological Evolution
Paper Details
References
  • References58
  • Citations56
12345...
  • References58
  • Citations56
12345...

Coding coenzyme handles: a hypothesis for the origin of the genetic code

Proceedings of the National Academy of Sciences of the United States of America

Nov 1, 1993

Eörs Szathmáry

PMID: 8234335

DOI:

Abstract

The coding coenzyme handle hypothesis suggests that useful coding preceded translation. Early adapters, the ancestors of present-day anticodons, were charged with amino acids acting as coenzymes of ribozymes in a metabolically complex RNA world. The ancestral aminoacyl-adapter synthetas...read more

Mentioned in this Paper

Amino Acyl-tRNA Synthetases
Catalytic RNA
Coenzymes
Transfer RNA
Introns

Related Papers

Paper Details
References
  • References58
  • Citations56
12345...
  • References58
  • Citations56
12345...

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