PMID: 9180218May 16, 1997Paper

Codistribution of the dopamine D3 receptor and glucocorticoid receptor mRNAs during striatal prenatal development in the rat

Neuroscience Letters
R DiazK Fuxe

Abstract

Glucocorticoids and dopamine (DA) may affect brain development and permanently programme central nervous system (CNS) responses. The ontogeny of the striatal glucocorticoid receptor (GR) mRNA and of DA D1, D2 and D3 receptor subtype mRNAs were, therefore, studied by means of in situ hybridization techniques. The expression of GR and the dopamine D3 receptor mRNAs but not of DA D1 and D2 receptor subtype mRNAs were observed in the striatal neuroepithelium during all prenatal stages studied (E14.5-E20.5). These results suggest that GR may directly influence striatal developmental processes, possibly involving the dopamine D3 receptor.

References

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Feb 1, 1973·Endocrinology·S MilkovićJ Paunović
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Citations

Mar 29, 2002·The Journal of Comparative Neurology·Sergey ZeleninRochellys Diaz Heijtz
Dec 12, 2001·Molecular and Cellular Endocrinology·J R Seckl
Jul 20, 2010·Toxicological Sciences : an Official Journal of the Society of Toxicology·Deborah A Cory-SlechtaSue Liu
Jan 30, 2013·Toxicological Sciences : an Official Journal of the Society of Toxicology·Deborah A Cory-SlechtaJoshua L Allen
Dec 18, 2001·Mechanisms of Development·Ursula M D'SouzaM Maral Mouradian

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