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Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responses

RNA Biology

Apr 22, 2015

Lauren EndresThomas J Begley

Abstract

tRNA (tRNA) is a key molecule used for protein synthesis, with multiple points of stress-induced regulation that can include transcription, transcript processing, localization and ribonucleoside base modification. Enzyme-catalyzed modification of tRNA occurs at a number of base and suga...read more

Mentioned in this Paper

Cell Cycle Progression
Establishment and Maintenance of Localization
Study
Biological Adaptation to Stress
Abnormal Degeneration
Translational Elongation
Genome
Attentional Bias
Gene Editing
Ribonucleosides
2
117
Paper Details
References
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  • Citations33
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tRNA modifications regulate translation during cellular stress

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Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responses

RNA Biology

Apr 22, 2015

Lauren EndresThomas J Begley

PMID: 25892531

DOI: 10.1080/15476286.2015.1031947

Abstract

tRNA (tRNA) is a key molecule used for protein synthesis, with multiple points of stress-induced regulation that can include transcription, transcript processing, localization and ribonucleoside base modification. Enzyme-catalyzed modification of tRNA occurs at a number of base and suga...read more

Mentioned in this Paper

Cell Cycle Progression
Establishment and Maintenance of Localization
Study
Biological Adaptation to Stress
Abnormal Degeneration
Translational Elongation
Genome
Attentional Bias
Gene Editing
Ribonucleosides
2
117

Feeds With Similar Papers

Chemoproteomics

Chemoproteomics is an approach to discovering mechanisms for regulating biological pathways for the purpose of designing new pharmaceutical therapies. Here is the latest research on this chemical proteomic method for pharmacological discovery research.

Proteogenomics

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Related Papers

FEBS Letters

tRNA modifications regulate translation during cellular stress

FEBS LettersOctober 12, 2014
Chen GuPeter C Dedon
Chemical Research in Toxicology

A system of RNA modifications and biased codon use controls cellular stress response at the level of translation

Chemical Research in ToxicologyJanuary 16, 2014
Peter C Dedon, Thomas J Begley
Paper Details
References
  • References100
  • Citations33
12345...
  • References100
  • Citations33
1234

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