Codon usage bias in herpesvirus

Archives of Virology
Minghui Fu

Abstract

In this study, I present a comprehensive analysis of codon usage bias in 43 herpesviruses for which the whole genome has been sequenced. The values of the effective number of codons revealed that the majority of the herpesviruses did not have high codon bias, with the exceptions of only simplexviruses and some varicelloviruses. The results of correspondence analysis, a plot of ENC and GC content at the third position of the codon and analysis of preferred codons all revealed that the codon bias was mainly influenced by nucleotide composition. This suggests that mutation pressure is the main factor influencing codon usage bias in herpesviruses.

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Citations

Jan 21, 2011·Virus Genes·Meng WangJie Zhang
Jun 20, 2013·Virus Genes·Gang LuWenhua Xiang
Jan 16, 2014·Indian Journal of Virology : an Official Organ of Indian Virological Society·Soumen Bhattacharjee
Apr 1, 2011·Virology Journal·Jie ZhangYong-sheng Liu
Mar 16, 2012·Virology Journal·Xin-sheng LiuYong-lu Wang
Feb 22, 2014·Archives of Virology·Ye ChenChong Wang
Sep 23, 2014·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Ye ChenChong Wang
Jul 17, 2019·Journal of Cellular Biochemistry·Pratichi SinghFebin Prabhu Dass J
Feb 10, 2020·Archives of Virology·Bornali DebSupriyo Chakraborty
Jun 23, 2021·Wiley Interdisciplinary Reviews. RNA·Eleanor R Gaunt, Paul Digard

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