Oct 11, 1988

Codon usage in Pseudomonas aeruginosa

Nucleic Acids Research
S E West, B H Iglewski


We have generated a codon usage table for Pseudomonas aeruginosa. Codon usage in P. aeruginosa is extremely biased. In contrast to E. coli and yeast, P. aeruginosa preferentially uses those codons within a synonymous codon group with the strongest predicted codon-anticodon interaction. We were unable to correlate a particular codon usage pattern with predicted levels of mRNA expressivity. The choice of a third base reflects the high guanine plus cytosine content of the P. aeruginosa genome (67.2%) and cytosine is the preferred nucleotide for the third codon position.

Mentioned in this Paper

Pseudomonas aeruginosa (antigen)
Sense Codon
Codon Genus
Codon (Nucleotide Sequence)
Pseudomonas aeruginosa
Genes, Bacterial

About this Paper

Related Feeds

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.