Oct 11, 1988

Codon usage in Pseudomonas aeruginosa

Nucleic Acids Research
S E West, B H Iglewski

Abstract

We have generated a codon usage table for Pseudomonas aeruginosa. Codon usage in P. aeruginosa is extremely biased. In contrast to E. coli and yeast, P. aeruginosa preferentially uses those codons within a synonymous codon group with the strongest predicted codon-anticodon interaction. We were unable to correlate a particular codon usage pattern with predicted levels of mRNA expressivity. The choice of a third base reflects the high guanine plus cytosine content of the P. aeruginosa genome (67.2%) and cytosine is the preferred nucleotide for the third codon position.

Mentioned in this Paper

Guanine
Pseudomonas aeruginosa (antigen)
Bacteriophages
Cytosine
Sense Codon
Codon Genus
Codon (Nucleotide Sequence)
Pseudomonas aeruginosa
Genes, Bacterial
Nucleotides

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