PMID: 376100May 1, 1979Paper

Coexistence of leukemic reticuloendotheliosis and histiocytic lymphoma: a case report

Cancer
S S AdlerH M Golomb

Abstract

A 65-year-old woman had pancytopenia, splenomegaly, and an inaspirable bone marrow. Diagnostic evaluation demonstrated that she had both leukemic reticuloendotheliosis (LRE), or hairy cell leukemia, and an additional lympho-reticular neoplasm, most likely a "histiocytic" lymphoma. The diagnosis of LRE was based on the histopathology of spleen tissue and of a bone marrow biopsy specimen. The diagnosis of diffuse "histiocytic" lymphoma was based on the histopathology of a splenic hilar and a mesenteric lymph node, tumor nodules in the kidney and spleen, and tissue from a mass obstructing a ureter. This is the first well-documented association of a second lympho-reticular neoplasm with LRE. Even relatively gently treatment of the "histiocytic" lymphoma resulted in fatal pancytopenia, illustrating the restricitons on therapy imposed by the marrow impairment due to the LRE.

References

Mar 29, 1975·Lancet·J G SinkovicsF Györkey
Jan 13, 1977·The New England Journal of Medicine·D W GoldeR H Stevens
Mar 1, 1976·Journal of the National Cancer Institute·J C BrouetM Seligmann
Nov 1, 1976·Cancer·M J DeeganB Schnitzer
Nov 23, 1974·Lancet·S E Salmon, M Seligmann
Feb 1, 1974·Journal of Chronic Diseases·R K KarchmerT D Chin
Oct 1, 1974·Cancer·R J Lukes, R D Collins
Feb 1, 1974·American Journal of Clinical Pathology·B Schnitzer, L Kass
Apr 6, 1957·British Medical Journal·M BURNET

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Citations

Nov 1, 1992·British Journal of Haematology·J MerciecaS Fairhead
Apr 1, 1983·Postgraduate Medical Journal·K M De CockB M Wankya
Feb 1, 1991·Urology·T Y Huang, L T Yam
Apr 1, 1985·American Journal of Hematology·E E VokesH M Golomb
Sep 15, 1985·Cancer·R H JacobsH M Golomb
Nov 15, 1985·Cancer·K M DavisR C Braylan
Jan 1, 1987·Critical Reviews in Oncology/hematology·J Jansen

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