Coexistence of mycobacterial infections - Mycobacterium tuberculosis and Mycobacterium leprae - in Sri Lanka: a case series.

Journal of Medical Case Reports
B S D P KeragalaC N Gunasekera

Abstract

Leprosy is one of the oldest mycobacterial infections and tuberculosis is the most common mycobacterial infection with a higher degree of infectivity than leprosy. Although both diseases are prevalent in clusters in developing countries, simultaneous occurrence of them in an individual is a rare entity, even in an endemic setting. We describe six cases of tuberculosis and leprosy coinfection: a 57-year-old Sinhalese woman, a 47-year-old Tamil woman, a 72-year-old Tamil man, a 59-year-old Sinhalese man, a 54-year-old Sinhalese man, and a 50-year-old Sinhalese man. In this case series, five patients had lepromatous leprosy and the majority of patients were men. Three patients were detected to have tuberculosis at the outset of treatment of leprosy, while two developed tuberculosis later and one had extrapulmonary tuberculosis 5 years before the diagnosis of leprosy. The latter developed pulmonary tuberculosis as a reactivation while on treatment for leprosy. A majority of our patients with pulmonary tuberculosis had positive Mantoux test, high erythrocyte sedimentation rate, radiological evidence, and acid-fast bacilli in sputum. Human immunodeficiency virus and diabetes were detected in one patient. One patient had rifampicin-re...Continue Reading

References

Sep 1, 1993·The Journal of Laryngology and Otology·P M Flanagan, J C McIlwain
Feb 7, 1998·American Journal of Public Health·T LietmanS Blower
Sep 29, 2000·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·D K AgarwalR K Gupta
May 26, 2004·BMJ : British Medical Journal·W Cairns S SmithJan Hendrik Richardus
Feb 8, 2006·Arthritis and Rheumatism·Susan S JickHyon K Choi
Jul 7, 2007·Journal of Medical Case Reports·Chandrashekhar T SreeramareddyPv Kishore
Jun 12, 2010·Lung India : Official Organ of Indian Chest Society·Rajendra PrasadGiridhar Hosmane
Dec 5, 2012·The American Journal of Tropical Medicine and Hygiene·Maria Ângela B TrindadeBernard Naafs

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Methods Mentioned

BETA
biopsy
X-ray
ESR
bronchoalveolar lavage

Software Mentioned

GeneXpert

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