Coexistence of Nerve Enlargement and Neuratrophy Detected by Ultrasonography in Leprosy Patients

Scientific Reports
Xiaohua ChenChunzhi Pan

Abstract

The purpose of this study was to evaluate peripheral neural impairment in leprosy patients by ultrasonography (US). The cross-sectional areas (CSAs) of the median (M), ulnar (U) and common fibular (CF) nerves were compared in 71 leprosy patients and 29 healthy controls, and the data were analyzed between the leprosy, multibacillary (MB)/paucibacillary (PB), reaction (R)/no reaction (NR), disability (D)/no disability (ND), and longer/shorter duration groups after treatment. We found that for the nerves located in upper limbs, the CSAs were significantly increased in the leprosy patients vs the controls; the PB group vs the MB group; the R group vs the NR group; the ND group vs the D group; and the longer duration group vs the shorter duration group at some positions of the M nerve and U nerve. In contrast, for the nerves located in lower limbs, the CSAs were significantly reduced in the leprosy patients vs the controls and in the longer duration group vs the shorter duration group at some positions of the CF nerve. This result indicated that nerve enlargement and neuratrophy coexist in leprosy patients.

References

Apr 15, 2004·Lancet·Warwick J Britton, Diana N J Lockwood
Nov 13, 2008·Nature Clinical Practice. Neurology·Einar P Wilder-Smith, Wim H Van Brakel
Aug 12, 2009·PLoS Neglected Tropical Diseases·Suman JainIndira Nath
Aug 28, 2009·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Jorge EliasAntonio Carlos dos Santos
Mar 17, 2011·PLoS Neglected Tropical Diseases·Estrella Lasry-LevyDiana N J Lockwood
May 28, 2011·The Lancet Infectious Diseases·Laura C Rodrigues, Diana Nj Lockwood
Jun 20, 2013·Memórias do Instituto Oswaldo Cruz·Marco Andrey Cipriani FradeNorma Tiraboschi Foss
Aug 13, 2013·Handbook of Clinical Neurology·Marcos R G de Freitas, Gérard Said
Jun 1, 2012·International Health·Diana N Lockwood, Paul R Saunderson
Dec 10, 2015·PLoS Neglected Tropical Diseases·Helena Barbosa LugãoMarco Andrey Cipriani Frade
Jan 17, 2016·Clinics in Dermatology·Suman JainSujai Suneetha
Jan 21, 2016·Polish journal of radiology·Yashant Aswani, Shenaz Saifi
Apr 19, 2016·Indian Journal of Dermatology, Venereology and Leprology·P Narasimha Rao, Sujai Suneetha
Nov 17, 2016·PLoS Neglected Tropical Diseases·Helena Barbosa LugãoMarcello Henrique Nogueira-Barbosa

❮ Previous
Next ❯

Citations

Mar 9, 2021·Radiology Case Reports·Helen ZhaoSyed I Alam
Apr 27, 2021·Acta Neurologica Scandinavica·Madhu NagappaHimanshu Mohan Kumar
Aug 26, 2021·Indian Dermatology Online Journal·Sujai K Suneetha, P Narasimha Rao

❮ Previous
Next ❯

Methods Mentioned

BETA
amputation

Software Mentioned

Prism
GraphPad Prism
GraphPad

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

PLoS Neglected Tropical Diseases
Helena Barbosa LugãoMarcello Henrique Nogueira-Barbosa
PLoS Neglected Tropical Diseases
Helena Barbosa LugãoMarco Andrey Cipriani Frade
© 2022 Meta ULC. All rights reserved