Coexisting intracranial tumors with pituitary adenomas: genetic association or coincidence?

Journal of Cancer Research and Therapeutics
Sunil V FurtadoAlangar S Hegde

Abstract

The co-occurrence of two or more brain tumors with different histological features is rare. The authors report three rare cases of intracranial tumors associated with pituitary adenomas. Two of the pituitary tumors were functioning adenomas: a prolactinoma and a thyrotropin secreting adenoma. Two of the associated intracranial neoplasms were gliomas and one was a meningioma. Radiological and clinical examination for syndromal association was negative in all cases. We briefly discuss the presentation and treatment options of these cases and review the 19 previous publications in the literature of pituitary tumors occurring in association with other neoplasms and explore the possible links underlying these co-occurring neoplasms. Our three cases represent 0.86% of all pituitary tumors operated at our institute over a 9-year period.

References

Feb 13, 2001·Cancer Genetics and Cytogenetics·M J BelloJ A Rey
Jan 16, 2007·Journal of Neurosurgery·Svetlana PravdenkovaMuhammad Husain
Nov 15, 2007·Pituitary·Alberto FernandezJohn A H Wass
Mar 12, 2008·Skull Base : Official Journal of North American Skull Base Society ... [et Al.]·Leodante B da CostaMichael Tymianski
Sep 25, 2008·Cases Journal·Vassilis SamarasCalypso Barbatis

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Citations

Sep 27, 2014·Journal of Neurosurgery·William T Couldwell, Lisa A Cannon-Albright
May 13, 2015·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Fernando Ruiz-JuretschkeEmilio Salinero
Apr 19, 2015·World Journal of Surgical Oncology·Duoduo ZhangHaiyan Huang
Dec 6, 2017·Journal of Neurosciences in Rural Practice·Vladimir Figueroa-AngelMaria Del Rocio Estrada-Hernandez
Jun 18, 2019·British Journal of Neurosurgery·Friso de VriesWouter R van Furth
Nov 30, 2019·International Journal of Endocrinology·Meng HaoAnand Vaidya
Feb 23, 2019·Journal of Surgical Case Reports·Abdulaziz AlshalawiAbdulaziz Alarifi
Oct 10, 2020·Surgical Neurology International·Jaskaran Singh GosalSudeep Khera
Apr 29, 2018·World Neurosurgery·Sohail SyedSteven A Toms

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